News

Olivia James, a Wellcome Trust PhD student in Dr. Mahima Swamy’s lab in the MRC PPU has been awarded the Dundee Prize for Molecular and Cellular Biology 2021.

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Mutations in PINK1 are the second most frequent cause of autosomal recessive early-onset Parkinson’s disease. PINK1 is activated upon mitochondrial damage to phosphorylate Ubiquitin and Parkin to stimulate Parkin E3 ligase activity, and this is critical for removal of damaged mitochondria by autophagy (mitophagy).

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Two researchers from the MRC PPU have been awarded places in the Scottish Universities Life Sciences Alliance (SULSA) Forging Futures Scheme.

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Miratul Muqit Portrait

The Royal Society’s first open access title, Open Biology, has reached its 10th Anniversary. To kick off a year of celebration, Subject Editors have highlighted their favourite articles from the past decade. Of the nine top publications selected, work from the research group of Miratul Muqit is being highlighted.

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Three PhD students from the MRC PPU have successfully made It through to the final round of the Biotechnology Young Entrepreneurs Scheme (YES).

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In 1998, mutations in the Parkin gene were discovered as a cause of early-onset Parkinson’s disease by a Japanese team who in collaboration with Keiji Tanaka then showed in 2000 that it functioned as a ubiquitin E3 ligase. However, the physiological substrates of Parkin remained elusive for many years.

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A collaborative study published in Nature from Tom Deegan (formerly a postdoc in Karim Labib’s lab, now a group leader at MRC HGU, Edinburgh) and Joe Yeeles’ lab

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Mutations in the gene encoding the CDKL5 kinase are among the most common genetic causes of childhood epilepsy and can also give rise to the severe neurodevelopmental condition CDD (CDKL5 Deficiency Disorder). Despite its importance for human health, the phospho–targets and cellular roles of CDKL5 are poorly understood.

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We are delighted to announce that Kirby Swatek will open an independent research laboratory in the MRC PPU at the beginning of 2022.

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MRC PPU researchers partnered with the Tropicalist Trust to run an event for school pupils in the upper reaches of the Himalayas, northern India to inspire them to consider a career in science.

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