Research | Publications

Multiple phosphorylation of the Cdc48/p97 cofactor protein Shp1/p47 occurs upon cell stress in budding yeast

Agrotis A, Lamoliatte F, Williams TD, Black A, Horberry R, Rousseau A

Principal Investigator(s):
Adrien Rousseau
2023
PubMed

The scientific career and life of Edmond H. Fischer, a personal tribute

Cohen, P

Principal Investigator(s):
Philip Cohen
2023
PubMed

Therapeutic validation and targeting of signalling networks that are dysregulated in intellectual disability

Bustos, F., & Findlay, G. M

Principal Investigator(s):
Greg Findlay
2023
PubMed

Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72-ALS iPSC-derived microglia contributes to neurodegeneration

Banerjee, P., Mehta, A.R., Nirujogi, R.S., Cooper, J., James, O.G., Nanda, J., Longden, J., Burr, K., Salzinger, A., Paza, E., Newton, J., Story, D., Pal, S., Smith, C., Alessi, D.R., Selvaraj, B.T., Priller, J., Chandran, S

Principal Investigator(s):
Dario Alessi
2023
PubMed

PIK3CA-related overgrowth: silver bullets from the cancer arsenal?

Madsen, R. R. & Semple, R. K.

Principal Investigator(s):
Ralitsa Madsen
2022
PubMed

Purification, crystallization and drug screening of the IRAK pseudokinases

Lange SM, Kulathu Y

Principal Investigator(s):
Yogesh Kulathu
2022
PubMed

The Immunological Proteome Resource

Alejandro J. Brenes, Jens L. Hukelmann, Laura Spinelli, Andrew J.M. Howden, Julia M. Marchingo, Linda V. Sinclair, Christina Rollings, Olivia J. James, Iain R Phair, Stephen P. Matthews, Sarah H. Ross, J. Simon C. Arthur, Mahima Swamy, David K. Finlay, Angus I. Lamond, Doreen A. Cantrell

Principal Investigator(s):
Mahima Swamy
2022
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Breast cancer stem cell-derived tumors escape from γδ T cell immunosurveillance in vivo by modulating γδ T cell ligands

Katrin Raute, Juliane Strietz, Geoffroy Andrieux, Oliver S. Thomas, Klaus M. Kistner, Marina Zintchenko, Peter Aichele, Houjiang Zhou, Wilfried Weber, Melanie Boerries, Mahima Swamy, Jochen Maurer, Susana Minguet

Principal Investigator(s):
Mahima Swamy
2022
PubMed
Alt Link

Structure-based design and characterization of Parkin activating mutations

Stevens, M.U., Croteau, N., Eldeeb, M.A., Zeng, Z.W., Toth, R., Durcan, T.M., Springer, W., Fon, E.A., Muqit, M.M.*, Trempe, J-F

Principal Investigator(s):
Miratul Muqit
2022
Alt Link

Elaboration of a MALDI-TOF Mass spectrometry-based assay of Parkin activity and High Throughput screening platform for Parkin activators

Traynor, R., Moran, J., Stevens, M.U., Knebel, A., Behrouz, B., Merchant, K., Hastie, C.J., Davies, P., Muqit, M.M., de Cesare, V

Principal Investigator(s):
Miratul Muqit, Virginia De Cesare
2022
Alt Link

Non-lysine ubiquitylation: Doing things differently

Kelsall, I.R

Principal Investigator(s):
Philip Cohen
2022
PubMed

Salt Inducible Kinase 2 regulates fibrosis during bleomycin induced lung injury

Gijsel-Bonnello, M., Darling, N.J., Tanaka, T., Marchesi, F., Thompson, S., Clark, K.,
Kurowska-Stolarskao, Cohen, P. and Arthur, J.S.C

Principal Investigator(s):
Philip Cohen
2022
PubMed

Identification of ester-linked ubiquitylation sites during TLR7 signalling increases the number of inter-ubiquitin linkages from 8 to 12

McCrory, E., Akimov, V., Cohen, P. and Blagoev, B

Principal Investigator(s):
Philip Cohen
2022
PubMed

Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC

Snelling, T., Shpiro, N., Gourlay, R., Lamoliatte, F. and Cohen, P

Principal Investigator(s):
Philip Cohen
2022
PubMed

TAK1 protein kinase activity is required for TLR signalling and cytokine production in myeloid cells

Rodrigues, M., Petrova, T., Tibbs, B., Arthur, J. S. and Cohen, P.

Principal Investigator(s):
Philip Cohen
2022
PubMed

Why are the phenotypes of TRAF6 knock-in and TRAF6 knock-out mice so different?

Petrova, T., Bennett, K., Nanda, S.K., Strickson, S., Scudamore, C. and Cohen, P.

Principal Investigator(s):
Philip Cohen
2022
PubMed

Spt5 histone binding activity preserves chromatin during transcription by RNA polymerase II

Evrin C, Serra-Cardona A, Duan S, Mukherjee PP, Zhang Z, Labib KPM

Principal Investigator(s):
Karim Labib
2022
PubMed

Multiple UBX proteins reduce the ubiquitin threshold of the mammalian

Fujisawa R., Polo Rivera C., Labib K

Principal Investigator(s):
Karim Labib
2022
PubMed

A CRISPR view on autophagy

Liang, J. R., & Corn, J. E

Principal Investigator(s):
Jin Rui (Amos) Liang
2022
PubMed

Comprehensive short and long read sequencing analysis for the Gaucher and Parkinson's disease-associated GBA gene

Toffoli M, Chen X, Sedlazeck FJ, Lee CY, Mullin S, Higgins A, Koletsi S, Garcia-Segura ME, Sammler E, Scholz SW, Schapira AHV, Eberle MA, Proukakis C

Principal Investigator(s):
Esther Sammler
2022
PubMed