We are delighted to announce that Jin Rui (Amos) Liang, who will open an independent research laboratory within the MRC PPU during the summer of 2022, has been awarded a highly sought after Career Development Fellowship from Cancer Research UK to study a novel association between endoplasmic reticulum-speci
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Ubiquitylation was discovered over 40 years ago as a mechanism that marks proteins for destruction by the proteasome. Since then, ubiquitylation has been found to regulate protein function in other ways, but the concept that proteins are the sole targets of ubiquitylation has never altered.
…moreJin Rui (Amos) Liang will open an independent research laboratory within the MRC PPU during the summer of 2022
…moreDr Nicola Darling, a senior postdoc in in Sir Philip Cohen’s lab in the MRC PPU, has been awarded the prestigious School of Life Sciences People’s Award.
…moreOlivia James, a Wellcome Trust PhD student in Dr. Mahima Swamy’s lab in the MRC PPU has been awarded the Dundee Prize for Molecular and Cellular Biology 2021.
…moreMutations in PINK1 are the second most frequent cause of autosomal recessive early-onset Parkinson’s disease. PINK1 is activated upon mitochondrial damage to phosphorylate Ubiquitin and Parkin to stimulate Parkin E3 ligase activity, and this is critical for removal of damaged mitochondria by autophagy (mitophagy).
…moreThe Royal Society’s first open access title, Open Biology, has reached its 10th Anniversary. To kick off a year of celebration, Subject Editors have highlighted their favourite articles from the past decade. Of the nine top publications selected, work from the research group of Miratul Muqit is being highlighted.
…moreThree PhD students from the MRC PPU have successfully made It through to the final round of the Biotechnology Young Entrepreneurs Scheme (YES).
…moreIn 1998, mutations in the Parkin gene were discovered as a cause of early-onset Parkinson’s disease by a Japanese team who in collaboration with Keiji Tanaka then showed in 2000 that it functioned as a ubiquitin E3 ligase. However, the physiological substrates of Parkin remained elusive for many years.
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