Welcome to the Kulathu Lab!
We are part of the MRC Protein Phosphorylation & Ubiquitylation Unit at the University of Dundee.
Research in the lab is focussed on discovering the fundamental principles of how cellular homeostasis is maintained by the ubiquitin system. Almost every cellular process in eukaryotes is regulated by the posttranslational modification of proteins with ubiquitin. In our research we use a multidisciplinary approach with techniques ranging from biochemistry, structural biology and proteomics to studies in model organisms to gain mechanistic and functional insights into ubiquitin signalling mechanisms in health and disease.
The two main biological questions we address are:
1. How is protein homeostasis maintained by the ubiquitin system?
2. How are T lymphocyte biology and adaptive immune responses regulated by ubiquitin signalling networks?
Find out more about our research here
Recent Lab News
The focussed meeting on Deubiquitinases was held in Edinburgh. With ~150 participants from 15 different countries, lots of exciting science this meeting was a big success. Next one in 2021?
Jayaprakash successfully graduates and gets his PhD. Congratulations Jay!
We bid farewell to Soo-Youn who moves to Birmingham to work on arginine methylation in cancer.
Yogesh Kulathu, Ph.D.
MRC PPU, School of Life Sciences
University of Dundee
Interested in joining the Kulathu lab?
If you are interested in our research and want to join the team, but don't find a specific position advertised, please send your inquiries to ykulathu (#!) dundee.ac.uk
We welcome applicants from all backgrounds and nationalities.