New Principal Investigator Greg Findlay Joins MRC-PPU
We are delighted to announce that Greg Findlay has opened his first independent laboratory here at the MRC Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU).
Greg comes to us from the Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada where he was a Postdoctoral Research Fellow in the laboratory of Tony Pawson. During his postdoctoral research studies Greg became interested in understanding signalling mechanisms that regulate cell-fate determination by analysing embryonic stem cell differentiation. One of the highlights was the discovery that the Grb2/Sos1 complex integrates a number of complex upstream signals to ensure that primitive endoderm specification occurs in a selective and timely manner, as is required during mammalian development. The manuscript reporting this work was recently published in Cell
In his new lab Greg's game-plan is to uncover novel protein kinase as well as protein ubiquitylation signalling networks controlling embryonic stem cell pluripotency.
Greg was a University of Dundee Biochemistry Undergraduate student (1997-2001) where he developed his interest in signal transduction by undertaking an honours project with MRC-PPU Principal Investigator Tricia Cohen. Greg then undertook his PhD with Richard Lamb at the Institute of Cancer Research on defining how the mTOR pathway was activated by amino acids (2002-2007), before moving to Tony Pawson's lab in 2007.
Greg comes to us from the Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada where he was a Postdoctoral Research Fellow in the laboratory of Tony Pawson. During his postdoctoral research studies Greg became interested in understanding signalling mechanisms that regulate cell-fate determination by analysing embryonic stem cell differentiation. One of the highlights was the discovery that the Grb2/Sos1 complex integrates a number of complex upstream signals to ensure that primitive endoderm specification occurs in a selective and timely manner, as is required during mammalian development. The manuscript reporting this work was recently published in Cell
In his new lab Greg's game-plan is to uncover novel protein kinase as well as protein ubiquitylation signalling networks controlling embryonic stem cell pluripotency.
Greg was a University of Dundee Biochemistry Undergraduate student (1997-2001) where he developed his interest in signal transduction by undertaking an honours project with MRC-PPU Principal Investigator Tricia Cohen. Greg then undertook his PhD with Richard Lamb at the Institute of Cancer Research on defining how the mTOR pathway was activated by amino acids (2002-2007), before moving to Tony Pawson's lab in 2007.