Previous Seminars and Lectures

Lecture Title Details
Seminar
Dr. Alex Gould
Francis Crick Institute
Cell-type specific tagging and tracing of metabolites in vivo

MSI-SLT
SCILLS Lecture
Prof. Vincent Tagliabracci
Howard Hughes Medical Institute
Expanding the kinome

MSI-SLT

Dr. Adam Grieve
University of Bristol
Biology in the bilayer: rhomboid proteases at synapses

MSI-SLT
Spotlight Seminar
Samantha Rickard
University of Auckland
Conformational selection by dasatinib for phosphorylated Y394 Lck provides a new mechanism to target the regulation of Lck-mediated immune response and new structures to support drug discovery

MSI-SLT
Seminar
Prof. Danny Huang
Beatson Institute for Cancer Research University of Glasgow
Non-proteinaceous ubiquitination by DELTEX family ubiquitin ligases

MSI-SLT
Seminar
Prof. Paul Elliott
University of Oxford, Department of Biochemistry
Understanding specificity within the ubiquitin/UBL cascade

MSI-SLT
Seminar
Prof. Peter Vangheluwe
KU Leuven
Targeting polyamines and polyamine transport in Parkinson’s disease and beyond

MSI-SLT
Seminar
Dr. Kirby Swatek
MRC PPU, University of Dundee
Insights into the ISG15 system – a multi-functional ubiquitin-like protein with critical roles in immunity

MSI-SLT
Seminar
Prof. Olga Vitek
Khoury College of Computer Sciences at Northeastern University, Boston
Best practice in proteomics data analysis and experimental design

Online via Teams
Seminar
Dr. Sila Ultanir
Francis Crick Institute
Epilepsy-linked kinase CDKL5 in brain development

MSI-SLT
Seminar
Dr. Maria Christophorou
Babraham Institute
Extracellular chromatin as a non-cell-autonomous regulator of cell fate transitions

MSI-SLT
Seminar
Prof. Benedikt Kessler
Target Discovery Institute, University of Oxford
Deubiquitinases (DUBs) modulate type-I interferon & IL-1b pathways

MSI-SLT
Dundee Cell Signalling Lecture
Prof. Alex Toker
Harvard Medical School
The PI 3-Kinase and AKT Signaling Pathway in Biology and Disease: From Discovery to Therapeutics

MSI-SLT
Seminar
Dr. Nuria Martinez Martin
Centro de Biologia Molecular Severo Ochoa (CBM-CSIC)
Mitochondrial dysfunction in B cells: a driver of an aged immune response

MSI-SLT
Seminar
Prof. Kathrin Lang
ETH Zurich
Expanding the genetic code – new tools for biology

Seminar
Dr. Martijn Luijsterburg
Leiden University Medical Centre, Netherlands
STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair

MSI-SLT
Seminar
Prof. Lukasz Bugaj
University of Pennyslvania
Perturb to understand: optical and thermal control of signaling and cell behavior

MSI-SLT
Seminar
Prof. Michael Rapé
University of California at Berkeley
Stress signaling at the crossroads of development and disease

MSI-SLT
Seminar
Dr. Marcus Taylor
Max Planck Institute for Infection Biology, Berlin
Deconstruction and Reconstruction of Signalosomes: Towards a Spatial Logic of Cellular Information Transfer

MSI-SLT
Seminar
Dr. Agostina Bertolin
Francis Crick Institute
How does the DNA Damage Checkpoint Protect Stalled DNA Replication Forks?

MSI-SLT
Seminar
Prof. Ivan Ahel
University of Oxford, Sir William Dunn School of Pathology
DELTEX E3 ligases ubiquitylate ADP-ribosyl modifications on proteins and nucleic acids

Online via Teams
Seminar
Prof. Simon Rousseau
McGill University, Montreal
Deciphering the molecular pathology of COVID-19 using multidimensional data from the Biobanque québécoise de la COVID-19 (BQC19)

CTIR 2.84 (The Murray Seminar Room), SLS
Seminar
Dr. Morgan Jones
MRC LMB
Visualising the Molecular Mechanisms of Chromosome Replication

MSI-SLT

Dr. Kirby Swatek
MRC PPU, University of Dundee
Irreversible inactivation of ubiquitin and ubiquitin-like proteins

MSI-SLT
Seminar
Dr. Gerardo Gamba
National Autonomous University of Mexico
Crosstalk between the calcium sensing receptor and the renal NaCl cotransporter, NCC

Seminar
Prof. Mina Ryten
UK-DRI Cambridge
Using long-read RNA sequencing to reveal the hidden transcriptome and even proteome in human brain

MSI-SLT
Seminar
Dr. Ryan Potts
Amgen, Inc.
‘Any target, every time’: how proximity-based therapeutics has redefined druggability

MSI-SLT
Seminar
Dr. Francesca Magrinelli
University College London
A New Gene for Early-Onset Parkinson’s Disease/Parkinsonism

MSI-SLT
Seminar
Prof. Zhongzhou Yang
Nanjing University China
Mechanistic study of heart development: PKB/Akt signaling and beyond

WTB-SR-1L2-110
Seminar
Dr. Richard Timms
Cambridge Institute of Therapeutic Immunology & Infectious Disease
Genetic tools to probe E3 ligase-substrate interactions

MSI-SLT

Dr. Bernhard Lechtenberg
Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, Australia
Non-canonical ubiquitination by HOIL-1 and other RBR E3 ubiquitin ligases

via Teams
Spotlight Seminar
Dr. Marija Maric
Francis Crick Institute
Exploring EXO1 nuclease-dependent cancer vulnerabilities using CRISPR-Cas9 dropout screening

MSI-SLT
Seminar
Prof. Gary Kleiger
University of Nevada, Las Vegas
Non-canonical protein ubiquitylation by the ARIH1 ubiquitin ligase

via Teams
Seminar
Prof. Eduardo Villablanca
Karolinska Institute
Decoding the initiation and resolution of inflammatory bowel diseases

CTIR 2.84 (The Murray Seminar Room), SLS
Seminar
Prof. Sandhya Visweswariah
Indian Institute of Science, Bangalore
Gut reactions and gut instincts: the role of cGMP

MSI-SLT
Seminar
Dr. Lina Herhaus
IBC II, Goethe University Frankfurt
Tumor immune evasion through IRGQ-directed autophagy

MSI-SLT
Seminar
Dr. Malte Gersch
Max Planck Institute of Molecular Physiology in Dortmund
Dissecting substrate selection mechanisms of deubiquitinating enzymes’

MSI-SLT
Seminar
Dr. Viktor Korolchuk
Biosciences Institute, University of Newcastle
‘Autophagy as a mechanism of oxidative stress response’

MSI-SLT
Spotlight Seminar
Dr. Paolo Gagliardi
Institute of Biology, University of Bern
Collective ERK activity waves in epithelial homeostasis and cancer

MSI-SLT

Dr. Joana Neves
Senior Lecturer in Mucosal Immunology, Kings College London
Complex organoid models to study gut cell interactions in health and disease

MSI-SLT
Seminar
Dr. Luke Fulcher
University of Oxford
Control of cell proliferation by the MDM2 mitotic timer: every double minute counts!

MSI-SLT
Seminar
Prof. Ian Gilmore
National Physical Laboratory, Nottingham
‘Metabolic imaging at the sub-cellular scale using mass spectrometry imaging – recent advances and challenges’

MSI-SLT
Seminar
Dr. Nisha Philip
Institute of Immunology and Infection Research, University of Edinburgh
Exploring the parasite ubiquitin machinery to block malaria transmission

MSI-SLT
Seminar
Dr. Fabian Coscia
Max Delbrück Centre, Berlin
Spatial tissue proteomics to assess health and disease

MSI-SLT
Seminar
Prof. Robert Semple
University of Edinburgh
‘Mind the Gap: Insulin resistance is much more than an insulin signalling disorder’

MSI-SLT
Seminar
Dr. Martina Foglizzo
University of Leeds
Exploring the structure and function of enzyme complexes involved in DNA repair and replication

MSI-SLT
Seminar
Dr. James Hurley
University of California, Berkeley
Structural Integration of Kinase, Phosphoinositide, and Rab Signaling in Autophagy Initiation

MSI-SLT
Seminar
Dr. Yasin Dagdas
Gregor Mendel institute of Molecular Plant biology in Vienna
Leveraging evolutionary diversity to discover new autophagy pathways in plants and humans

MSI-SLT
Seminar
Prof. Jonathan Pruneda
Oregon Health & Science University
Pathogenic bacteria make surgical strikes on host ubiquitin signaling

MSI-SLT
Seminar
Dr. Nazma Malik
The Salk Institute, La Jolla, California, USA
AMPK phosphorylation of FNIP1 dictates the kinetics of lysosome and mitochondrial biogenesis

CTIR 2.84 (The Murray Seminar Room), SLS
Seminar
Prof. Vincenzo D'Angiolella
Oxford Institute for Radiation Oncology
‘Modulation of E3 ubiquitin ligase activity in cell cycle and cancer: classical oscillations and neomorphic mutations’

MSI-SLT
Seminar
Ingrid Wertz
Lyterian Therapeutics
Co-opting the Ubiquitin System for Therapeutic Benefit

MSI-SLT
Seminar
Christina Buchanan
Neurology Department, Auckland City Hospital
A single pathogenic pink1 gene variant is a common cause of early-onset parkinson’s disease in people of western polynesian ethnicities

CTIR 2.84 (The Murray Seminar Room), SLS
Seminar
Prof. Anne Grünewald
University of Luxembourg
‘LRRK2 G2019S as trigger of inflammatory signaling in patient-derived microglia’

MSI-SLT
Seminar
Dr. Iain Fraser
Laboratory of Immune System Biology, National Institute of Allergy and Infectious Disease, National Institutes of Health, USA
‘Systems Biology Approaches to Dissecting the Macrophage Inflammatory Response’

MSI-SLT
Seminar
Prof. Masato Kanemaki
Department of Chromosome Science, National Institute of Genetics, Mishima, Japan
‘Exploring human DNA replication with an improved auxin-inducible degron technology’

MSI-SLT
Seminar
Dr. Paul Elliott
University of Oxford
BRUCE Almighty

MSI-SLT
Seminar
Dr. Leo James
MRC LMB
Trim-Away: Targeted degradation of pathogens and proteins

MSI-SLT
Seminar
Dr. Gwo-Tzer Ho
University of Edinburgh
The Mitochondria in Inflammatory Bowel Disease (IBD): From Bench to Bedside

MSI-SLT
Seminar
Prof. Michel Desjardins
Département de pathologie et biologie cellulaire, Université de Montréal
Parkinson’s disease-proteins regulate a stress response leading to autoimmunity and cell death

MSI-SLT
Spotlight Seminar
Dawafuti Sherpa
Max Planck Institute of Biochemistry Munich
‘Structural and mechanistic insights of GID E3 ubiquitin ligase’

MSI-SLT
Seminar
Prof. John Diffley
Francis Crick Institute
‘How DNA Replication Initiates and What Happens When it Goes Wrong’

MSI-SLT
Seminar
Prof. Ron Kopito
Stanford University
‘Proteostasis in the ER: A tale of two Ubs’

MSI-SLT
SCILLS Lecture
Dr. Tom Rapoport
Harvard Medical School
‘Mechanism of ER-associated protein degradation (ERAD)’

MSI-SLT
Seminar
Prof. Ruben Fernández-Busnadiego
University Medical Center Goettingen
‘Unravelling the structure of toxic protein aggregates in situ’

MSI-SLT
Seminar
Dr. Farhat Din
Edinburgh University
‘Colorectal Cancer Prevention Research’

Edinburgh
Seminar
Dr. Adrian Saurin
Jacqui Wood Cancer Centre
“Simple solutions to complex problems: from cell cycle regulation to anti-cancer treatments”

University of Dundee, Ninewells
Seminar
Dr. Chiara Maniaci
University of Newcastle
Cleave to modify: shining light on the dark proteome
-
MSI SLT
Seminar
Prof. Ron Hay
GRE, University of Dundee
Translating the SUMO signal into biological outputs

MSI SLT / Teams
Seminar
Prof. Ivan Đikić
Goethe University Frankfurt am Main
Ubiquitination and Autophagy in health and disease

Seminar
Prof. Satpal Virdee
MRC PPU, University of Dundee
Non-lysine ubiquitination and deubiquitination
-
Via Zoom
Seminar
Dr. David Murray
University of Dundee
Cell organization as a program of trafficking
-
Via Teams (in person by request to mrc-admin@dundee.ac.uk)
Seminar
Dr. Felix Randow
MRC Laboratory of Molecular Biology
How cells defend their cytosol against bacteria: Ubiquitylation of LPS and other tricks
-
Via Zoom