The SCottish Institute for ceLL Signalling (SCILLS) became a reality on October 1st 2008. With initial funding of £2 million per annum over the next five years from the Scottish Funding Council, its initial goal is to establish a Protein Ubiquitination Unit (PUU) dedicated to understanding the role of ubiquitination and related modifications in cell regulation and human disease. The PUU is housed on the 4th floor of the Sir James Black Centre at the University of Dundee, one floor above the MRC Protein Phosphorylation Unit with which it will interact closely, and is part of the College of Life Sciences Research Complex