Additional PhD Projects available to undertake within MRC-PPU


Please note that the deadline for applying for these projects is 2nd June. These positions are also open to EU and non-EU applicants. It is expected the student would be able to take up the studentship in Autumn 2017.

New biomarkers for Parkinson’s disease based on dissection of LRRK2 kinase biology.
Prof. Dario Alessi & Dr. Miratul Muqit (MRC-Unit)

Exploiting ERK5 signalling in regenerative medicine: a novel route to cardiac regeneration.
Dr. Greg Findlay (MRC-Unit) & Dr. Marios Stavridis (School of Life Sciences)

Activating MINDY DUBs to induce proteotoxic stress: A new strategy to kill cancer cells.
Dr. Yogesh Kulathu (MRC-Unit) & Prof. Vicky Cowling (School of Life Sciences)

Elaboration of small molecule activators of PINK1 kinase and Parkin E3 ligase for improved therapies in Parkinson's disease.
Dr. Miratul Muqit & Prof. Dario Alessi (MRC-Unit)

Drugging the undruggable with novel proteolytic AdPROM (Affinity-directed PROtein Missile) technology.
Dr. Gopal Sapkota (MRC-Unit) & Prof. Alessio Ciulli (School of Life Sciences)

Understanding how DNA repair nucleases remove chromosome tangles to prevent chromosomal instability and disease.
Prof. John Rouse (MRC-Unit) & Dr. Anton Gartner (School of Life Sciences)

Selective inhibitors of E3 ubiquitin ligases to treat neurodegenerative diseases.
Dr. Satpal Virdee (MRC-Unit) & Prof. Daan van Aalten (School of Life Sciences)