A quick google search for ‘kinase profiling' yields the International Centre for Kinase Profiling (ICKP), housed in the MRC-PPU as the top-hit. Established as a service in 1998, the ICKP works with academic labs, biotechnology and pharmaceutical companies to provide a reliable, rapid and cost-effective means to interrogate a customer's compound of interest against a broad panel of protein and lipid kinases.
Kinases are the pharmaceutical industry's most important class of drug target, yet one of the primary challenges is to develop a drug that selectively suppresses the activity of one, or at most a few, of the 500 protein kinases encoded by the human genome. As the MRC-PPU is home to the world's leading experts on kinases and phosphorylation, evolution of the ICKP was a natural one.
The recent face-lift of the website, though seemingly cosmetic, goes more than skin-deep. It was focused on streamlining access to the critical information about the ICKP's services and expertise more readily. The hope is that this will in turn ensure that scientists world-wide can interrogate their compound of interest more quickly, thereby accelerating their research.
The ICKP has always offered several ranges of kinase screens (Premier, Express, and Lipid) and has added a ‘Custom' screen to assist researchers to better tailor their screen. In addition to these services, staff at the ICKP can assist with IC50 determination, ATP Competition Assays, and Substrate Screens.
To visit the International Centre for Kinase Profiling website and identify the service that best suits your research please visit http://www.kinase-screen.mrc.ac.uk/ and please do spread the word to your colleagues and collaborators.
ICKP staff welcome your comments and suggestions on how to improve the site further. Please send all of your suggestions, no matter how minor, to kinase-screen@dundee.ac.uk
Kinases are the pharmaceutical industry's most important class of drug target, yet one of the primary challenges is to develop a drug that selectively suppresses the activity of one, or at most a few, of the 500 protein kinases encoded by the human genome. As the MRC-PPU is home to the world's leading experts on kinases and phosphorylation, evolution of the ICKP was a natural one.
The recent face-lift of the website, though seemingly cosmetic, goes more than skin-deep. It was focused on streamlining access to the critical information about the ICKP's services and expertise more readily. The hope is that this will in turn ensure that scientists world-wide can interrogate their compound of interest more quickly, thereby accelerating their research.
The ICKP has always offered several ranges of kinase screens (Premier, Express, and Lipid) and has added a ‘Custom' screen to assist researchers to better tailor their screen. In addition to these services, staff at the ICKP can assist with IC50 determination, ATP Competition Assays, and Substrate Screens.
To visit the International Centre for Kinase Profiling website and identify the service that best suits your research please visit http://www.kinase-screen.mrc.ac.uk/ and please do spread the word to your colleagues and collaborators.
ICKP staff welcome your comments and suggestions on how to improve the site further. Please send all of your suggestions, no matter how minor, to kinase-screen@dundee.ac.uk