Most Cited paper
The Biochemical Journal have announced that a paper published by Kris Clark in 2011, when he was a Postdoctoral Fellow in Philip Cohen's lab, is the most cited paper published in the Signal subsection of the journal over the two year period ending July 2013.
The paper, published in Biochem J. (2011) 434, 93-104 , describes the discovery of a novel feedback control pathway by which the IKK-related kinases, TBK1 and IKKepsilon, restrict the activation of the canonical IKK complex to prevent the overproduction of pro-inflammatory cytokines. Kris Clark subsequently found that this feedback control device is critical to prevent autoimmune disease: Clark et al, 2011, PNAS 108, 17093-17098.
For these and other discoveries Kris has previously received an Early Career Development Award from the Biochemical Society , and was recently awarded a Career Development Fellowship from Arthritis UK.
The paper, published in Biochem J. (2011) 434, 93-104 , describes the discovery of a novel feedback control pathway by which the IKK-related kinases, TBK1 and IKKepsilon, restrict the activation of the canonical IKK complex to prevent the overproduction of pro-inflammatory cytokines. Kris Clark subsequently found that this feedback control device is critical to prevent autoimmune disease: Clark et al, 2011, PNAS 108, 17093-17098.
For these and other discoveries Kris has previously received an Early Career Development Award from the Biochemical Society , and was recently awarded a Career Development Fellowship from Arthritis UK.