Philip Leverhulme Award


Dario Alessi, of the Medical Research Council Protein Phosphorylation Unit, has rounded off an extraordinary year by winning the sixth high profile award of his career and the fourth this year.

Dario secured a highly prestigious Philip Leverhulme Award - one of only 24 awards made annually, and will use his £50,00 prize money to design chemical compounds to generate drugs that target PDK1. In collaboration with his colleague Daan van Aalten, Dario mapped the atomic structure of PDK1, and this information will enable the design of drugs to specific parts of it. Five years ago Dario discovered PDK1, which controls both the growth of cells and how they respond to insulin.

The Leverhulme Trust provides £25 million each year to promote research of originality and significance principally in the university sector across a full span of disciplines.