Action

ALK, MET

Alt Name

Approval Jurisdiction

2011 FDA

Approved for clinical use

NSCLC with Alkmutation

Brutto

C₂₁H₂₂Cl₂FN₅O

CAS

877399-52-5

Commercial Vendor

Pfizer

Compound Image

Crizotinib.png

Compound name

Crizotinib

InChI

InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1

InChI Key

KTEIFNKAUNYNJU-GFCCVEGCSA-N

PubChem CID

11626560

Reference

Reference 2

SMILES

CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N

Approved Drug List

1