Action

CDK4/6

Alt Name

Approval Jurisdiction

2015 FDA 2016 EMA

Approved for clinical use

Advanced (metastatic) breast cancer

Brutto

CAS

571190-30-2

Commercial Vendor

Pfizer

Compound Image

Palbociclib.png

Compound name

Palbociclib

InChI

InChI=1S/C24H29N7O2/c1-15-19-14-27-24(28-20-8-7-18(13-26-20)30-11-9-25-10-12-30)29-22(19)31(17-5-3-4-6-17)23(33)21(15)16(2)32/h7-8,13-14,17,25H,3-6,9-12H2,1-2H3,(H,26,27,28,29)

InChI Key

AHJRHEGDXFFMBM-UHFFFAOYSA-N

MW

447.50

PubChem CID

5330286

Reference

Reference 2

SMILES

CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C

Approved Drug List

1