Action

MEK/RAF

Alt Name

Approval Jurisdiction

2018 FDA 2018 EMA

Approved for clinical use

BRAF mutant melanoma

Brutto

CAS

606143-89-9

Commercial Vendor

Array-Novartis-Pfizer

Compound Image

Binimetinib.png

Compound name

Binimetinib

InChI

InChI=1S/C17H15BrF2N4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)

InChI Key

ACWZRVQXLIRSDF-UHFFFAOYSA-N

MW

441.20

PubChem CID

10288191

Reference

Reference 2

SMILES

CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)F)C(=O)NOCCO

Approved Drug List

1