Action

CSF1R; c-KIT; FLT3

Alt Name

Approval Jurisdiction

2019 FDA

Approved for clinical use

Tenosynovial giant cell tumour

Brutto

CAS

1029044-16-3

Commercial Vendor

Daiichi Sankyo

Compound Image

Pexidartinib.png

Compound name

Pexidartinib

InChI

InChI=1S/C20H15ClF3N5/c21-15-6-16-14(10-28-19(16)29-11-15)5-12-2-4-18(26-7-12)27-9-13-1-3-17(25-8-13)20(22,23)24/h1-4,6-8,10-11H,5,9H2,(H,26,27)(H,28,29)

InChI Key

JGWRKYUXBBNENE-UHFFFAOYSA-N

MW

417.80

PubChem CID

25151352

Reference

Reference 2

SMILES

C1=CC(=NC=C1CC2=CNC3=C2C=C(C=N3)Cl)NCC4=CN=C(C=C4)C(F)(F)F

Approved Drug List

1