Action

JAK1

Alt Name

Approval Jurisdiction

2019 FDA 2019 EMA

Approved for clinical use

Rheumatoid arthritis

Brutto

CAS

1310726-60-3

Commercial Vendor

AbbVie

Compound Image

Upadacitinib.png

Compound name

Upadacitinib

InChI

InChI=1S/C17H19F3N6O/c1-2-10-7-25(16(27)24-9-17(18,19)20)8-11(10)13-5-22-14-6-23-15-12(26(13)14)3-4-21-15/h3-6,10-11,21H,2,7-9H2,1H3,(H,24,27)/t10-,11+/m1/s1

InChI Key

WYQFJHHDOKWSHR-MNOVXSKESA-N

MW

380.40

PubChem CID

58557659

Reference

Reference 2

SMILES

CCC1CN(CC1C2=CN=C3N2C4=C(NC=C4)N=C3)C(=O)NCC(F)(F)F

Approved Drug List

1