Dates: September 2006-November 2010

Current Position: Scientific Advisor, Fishawack Health

Publications Generated While in the Lab:

Pearce LR, Sommer EM, Sakamoto K, Wullschleger S, Alessi DR. (2011) Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney.

Biochem J. 436(1):169-79

Pearce LR, Alton GR, Kath JC, Lingardo L, Chapman J, Hwang C, Ermolieff J, Alessi DR (2010) Characterisation of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1). Biochem. J. 431: 245-255

Pearce LR, Kommander D, Alessi DR (2010) The nuts and bolts of AGC protein kinases. Nat. Rev. Mol. Cell Biol. 11(1):9-22



Alessi DR, Pearce LR, Garcia-Martinez JM (2009) New insights into mTOR signaling: mTORC2 and beyond. Sci. Signal. 2: pe27

Pearce LR, Huang X, Boudeau J, Pawlowski R, Wullschleger S, Deak M, Ibrahim AF, Gourlay R, Magnuson MA, Alessi DR (2007) Identification of Protor as a novel Rictor-binding component of mTORC2. Biochem. J. 405: 513-22