A third form of protein phosphatase 1 has been identified in skeletal muscle which is distinct from the species composed of the catalytic subunit complexed to the glycogen-binding subunit (protein phosphatase 1G) or inhibitor-2 (protein phosphatase 1I). The third form has an apparent molecular mass of 110 kDa, is not immunoprecipitated by antibody prepared against the glycogen-binding subunit, does not interact with glycogen and is devoid of inhibitor-2. It is tightly bound to myosin and is therefore termed protein phosphatase 1M.
Author(s):
Chisholm, A. A., Cohen, P.
PubMed:
2830909
Citation:
Chisholm, A. A., Cohen, P.
Chisholm, A. A., Cohen, P.
Biochim Biophys Acta
1988
968
392-400
PMID: 2830909