Publications | ZAP70 holds the key to kinetic proofreading for TCR ligand discrimination

A key biochemical event that enables T cells to discriminate between TCR antigens of varying affinities and to respond only to high-affinity antigens is full activation of the kinase ZAP70.

Principal Investigator(s):

Author(s):
Swamy, M

PubMed:
36045188
Citation:
Swamy, M
Nature Immunology
2022
Aug
doi:
10.1038/s41590-022-01297-w
PMID: 36045188