Lab Member | Anudharan Balendran

PhD Student

Anudharan Balendran Portrait
Past Lab Member

Date: October 1997 - January 2001

Current Position: External Innovation Director, Cardiovascular and Metabolism IMED, AstraZeneca Gothenburg, Sweden

Publications Generated While in the Lab:

1. Balendran, A., Casamayor, A., Deak, M., Paterson, A., Gaffney, P., Currie, R., Downes, C.P. & Alessi, D.R. (1999). PDK1 and PDK2 may be the same enzyme; PDK1 displays PDK2 activity in the presence of a synthetic peptide. Curr. Biol. 9, 393-404.

2. Balendran, A., Currie, R.A., Armstrong, C.G. &Avruch & Alessi, D.R (1999). Evidence that PDK1 mediates the phosphorylation of p70 S6 kinase in vivo at Thr412 as well as Thr252. (3 citations). J. Biol. Chem. 274, 37400-37406.

3. Hajduch, E., Rencurel, F., Balendran, A., Batty, I.H., Downes, C.P. & Hundal, H.S. (1999). Serotonin (5-HT), a novel regulator of glucose transport in rat skeletal muscle. J. Biol. Chem. 274, 13563-13568.

4. Williams, M., Arthur, J.S.C., Balendran, A., Van der kaay, J., Poli, V., Cohen, P. & Alessi, D.R. (2000). The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells. Curr. Biol. 10, 439-448.

5. Balendran, A., Biondi, R.M., Cheung, P., Casamayor, A., Deak, M. & Alessi. D.R, (2000). A PDK1 docking site is required for the phosphorylation of PKC zeta and PRK2 by PDK1. J. Biol. Chem. 275, 20806-20813.

6. Balendran, A., Hare, G.R., Kieloch, A., Williams, M.R. and Alessi, D.R. (2000). Further evidence that 3-phosphoinositide dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of Protein Kinase C (PKC) isoforms. FEBS Lett. 484, 217-223.

7. Hajduch, E., Balendhran, A., Batty, I.H., Litherland, G.J., Blair, A.S., Downes, C.P. & Hundal, H.S. (2001). Ceramide impairs the insulin-dependent membrane recruitment of Protein Kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells. Diabetologia 44, 173-183.