Lab Member | Beatrice Maria Filippi

Postdoctoral Researcher

Beatrice Maria Filippi  Portrait
Past Lab Member

Date: September 2007 - October 2010

Current Position: University Academic Fellow, School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, UK

Publications Generated While in the Lab:

MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases.

Filippi BM, de Los Heros P, Mehellou Y, Navratilova I, Gourlay R, Deak M, Plater L, Toth R, Zeqiraj E, Alessi DR.

EMBO J. 2011 May 4;30(9):1730-41

Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation.

Zeqiraj E, Filippi BM, Deak M, Alessi DR, van Aalten DM.

Science. 2009 Dec 18;326(5960):1707-11

ATP and MO25alpha regulate the conformational state of the STRADalpha pseudokinase and activation of the LKB1 tumour suppressor.

Zeqiraj E, Filippi BM, Goldie S, Navratilova I, Boudeau J, Deak M, Alessi DR, van Aalten DM.

PLoS Biol. 2009 Jun 9;7(6):e1000126

Novel role for the LKB1 pathway in controlling monocarboxylate fuel transporters.

Filippi BM, Alessi DR.

J Cell Biol. 2008 Oct 6;183(1):7-9

Country of Origin: Italy
Beatrice Maria