Date: October 2000-October 2003

Current Position: Policy Officer for Corporate Governance, University of Dundee

Publications Generated While in the Lab:

1. Thomas, C.C., Dowler, S., Deak, M. Alessi, D.R. van Aalten, D.M.F. (2001) Crystal structure of the phosphatidylinositol (3,4)-bisphosphate binding PH domain of TAPP1 - molecular basis of lipid specificity. Biochem. J. 358, 287-294.

2. Thomas, C.C., Deak, M., Alessi, D.R. and van Aalten, D.M.F. (2002) High resolution structure of the pleckstrin homology domain of protein kinase B/Akt bound to phosphatidylinositol (3,4,5)-trisphosphate. Current Biology 12, 1256-1262.

3. Biondi, R.M., Komander, D., Thomas, C.C., Lizcano, J.M., Deak, M., Alessi, D.R. and van Aalten, D.M.F. (2002) High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site. EMBO J 21, 4219-4228.

4. Milburn, C.C., Deak, M., Kelly, S.M., Price, N.C., Alessi,D.R. and van Aalten, D.M.F. (2003) Binding of phosphatidylinositol 3,4,5-trisphosphate to the Pleckstrin Homology domain of protein kinase B induces a conformational change.Biochem J. 375, 531-538.

5. Milburn, C.C., Boudeau, J., Deak, M., Alessi, D.R. & van Aalten, D.M.F. (2004) Crystal structure of MO25a in complex with the C-terminus of the pseudokinase STE20-Related ADaptor (STRAD). Nature Structural Biology 11, 193-200