Much research in the MRC PPU over the last 11 years has focused on understanding the roles of the LKB1 tumour suppressor protein kinase, as loss of function mutations in this enzyme are frequently observed to promote cancer. Some progress has been ma …more

Three teams of researchers – that include Dario Alessi and John Rouse – have received £16.99 million from the Wellcome Trust and the Medical Research Council (MRC) to bolster research into devastating neurodegenerative diseases …more

A paper published by Sir Philip Cohen and members of his research team in 2000 has been named as Europe's most influential publication over the period 1996-2007 in an article published in the September 2009 issue of Lab Times using information in Tho …more

Elton Zeqiraj, who has been working jointly in the labs of Daan van Aalten and Dario Alessi for nearly the last 4 years on structural analysis of the LKB1 complex, has been awarded his PhD. Pictured is Elton celebrating his success with his two exami …more

Charlotte Green, a graduate student co-supervised by Harinder Hundal (Division of Molecular Physiology, College of Life Sciences, University of Dundee) and Kei Sakamoto (MRC Protein Phosphorylation Unit), successfully defended her PhD thesis entitled …more

Jacob Thastrup, working in Dario Alessi's lab, has been awarded a PhD for work carried out on analysis of the function and regulation of WNK isoforms. Pictured is Jacob next to his parents, Ole and Lise Birgitte, and his examiners Dr Pat Eyers, YCR I …more

There has been much interest in studying the function and regulation of the Leucine Rich Repeat Protein Kinase-2 (LRRK2) which is mutated in a significant number of Parkinson's disease patients. Progress in this area has been slow and hampered by a l …more

We are now recruiting for PhD studentships to start in 2010. Information on the available projects can be found here . Please click here for how to apply. The closing date is October 30 2009 …more

At this year's Edinburgh Science festival, MRC PPU students Laura Pearce, Laura Brown, Hilary Smith, Eris Duro and Hosea Handoyo ran an activity showing how a blood cancer can be cured by blocking the 'Bcr-Abl' kinase with the medicine Gleevec. The  …more

New postdoc position in Dario Alessi's group currently being advertised, closing date 31st August 2009. For more info please click here …more