The Royal Society open access journal, Open Biology, recently celebrated its 5th anniversary. Amongst the Editor’s picks was the journal’s most cited article by former PhD student, Chandana Kondapalli, which to date has garnered 240 citations since it was published in 2012.

Chandana, who was supervised by Miratul Muqit and Dario Alessi, discovered the first bona fide substrate of the Parkinson’s linked kinase PINK1, namely Parkin, and mapped the phosphorylation site to a highly conserved N-terminal residue Serine65. In the paper Chandana also provided the first evidence that PINK1 was activated by mitochondrial depolarisation.

To read a copy of Chandana’s paper click here.