Prof. Daan van Aalten, Programme Leader at the MRC Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU) based at The University of Dundee, has been focused on the function of a novel post-translational modification, O-GlcNAcylation, for …more
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Dr. Helen Walden, Programme Leader of the MRC Protein Phosphorylation and Ubiquitylation Unit (MRC PPU) based at The University of Dundee, has been focused on understanding the intricate molecular architecture of proteins for over 10 years. …more
The lysosome acts as the stomach of the cell in that it digests and recycles unwanted, damaged or toxic cellular components. This is a vital process for the cell and prevents accumulation of 'junk' that can have devastating consequences as is becomin …more

Luke Fulcher, who recently graduated from University of Dundee with a BSc in (1st class) in Physiological Sciences, is due to start a PhD in the MRC PPU this coming August. Luke's has just been awarded The Queen's College Scholarship Award from Unive …more

Trametinib, a drug that inhibits the protein kinase MEK, has been found to increase the lifespan of fruit flies by 10%. If the drug has a similar effect in homo sapiens then it might prolong life by as much as 10 years, causing this discovery to mak …more

Alban Ordureau, a former student and postdoc in Philip Cohen's lab in the MRC-PPU (2007-2012) has been awarded a prestigious Lefler Fellowship to continue his research at Harvard medical School, Boston, USA, which is aimed at clarifying the molec …more
Understanding the mechanisms of Parkinson's disease remain a major biomedical challenge since the disease is on the rise and there remain no treatments that can cure or slow it down.
Over the last few years research in the Muqit lab h …more
Over the last few years research in the Muqit lab h …more

Congratulations to Julien Peltier and Matthias Trost for receiving the Thermo Scientific TMT Research Awar …more

Congratulations are due to Marija Maric, who has just been awarded the Pontecorvo Prize for 2014, for her discovery that the end of chromosome replication is regulated by ubiquitylation and the p97 ATPase. Marija completed her PhD studies last year i …more