Daan van Aalten and his research group working on carbohydrate signalling in mammalian cells have joined the MRC-PPU.

Daan's work on the regulation and function of the O-GlcNAc modification and how this impacts on biological processes rela …more

A team of postgraduate students from the College of Life Sciences at the University of Dundee has won the Scottish round of the Biotechnology Young Entrepreneurs Scheme (YES) qualifying them for the finals in London in December.

 …more

http://www.kinase-screen.mrc.ac.uk/kinase-inhibitors



Protein kinases are one of the pharmaceutical industry's most important classes of drug target. Nineteen protein kinase inhibitors have been approved for clinical use and ov …more

Jamie Wilson from the MRC PPU was one of the four joint winners of this year's poster exhibition by PhD students in College of Life Sciences entering their 3rd year. Jamie, who has trained as a pathologist, is currently a Wellcome Trust Clinical Fell …more

Well done to Gerta Hoxhaj for her successful PhD viva, held on October 5th 2012 on her work on the E3 ubiquitin ligase ZNRF2. (Hoxhaj is pronounced HOJ-EYE with a long O, and 'XH' in the Albanian alphabet sounds like 'J').

Gerta is Carol …more

Research carried out by Kris Clark in the MRC-PPU has identified a major fundamental mechanism controlling immune cell function that suggests a new approach to the development of drugs to treat inflammatory diseases. The  …more

Mutations leading to inappropriate activation of Akt isoforms contribute to proliferation and survival of a significant proportion of human cancers. Akt is activated by phosphorylation of its T-loop residue (Thr308) by the 3-phosphoinositide dependen …more

Fiona Brown who works in the Division of Signal Transduction Therapy Unit is participating in a very major charity event that is taking place this Saturday called Strictly Come Dance for Insight.



Fiona with her partner Scott  …more

The Infections and Immunity Board of the UK Medical Research Council (MRC) has awarded a grant of almost £1.5 million to Philip Cohen and his team to carry out research over the next five years on the mechanisms that prevent inflammatory and autoimmu …more

The International Centre for Kinase Profiling launched a new lipid kinase profiling service on 1st July 2012. These 17 lipid kinases will compliment the protein kinase profiling panel of 139 enzymes.

The lipid kinase panel includes PI3Kina …more