To launch the Medical Research Council (MRC) centenary celebrations, its chief executive Sir John Savill, gave an inspirational presentation on the history and past achievements of this fabulous organisation that has thus far supported the work that  …more

Gopal Sapkota has published a single-author research paper in Open BIology that puts a question mark on the notion that transforming growth factor beta (TGFÃ_Â_) activates TGFÃ_Â_ Activated Kinase 1 (TAK1).



The activation of p …more

The MRC-PPU hosted a visit by Mr Mike Nithavrianakis, British Deputy High Commissioner in Chennai. After an introduction from Miratul Muqit about the Unit, the Deputy High Commissioner met Sourav Banerjee, a PhD student in Dario Alessi's  …more

Several MRC-PPU researchers pictured before the race, took part in the the 10 km Monikie Run in aid of Diabetes research.

Results from right to left were:

-Paola de los Heros (Dario Alessi lab) Time: 59:29 min

-France …more

Alex Varshavsky from the California Institute of Technology, USA delivered the 5th SCILLS Lecture today May 1 2013. He presented work on recent discoveries about the ubiquitin system and the N-end rule pathway.



The 'SCILLS Lec …more

The majority of human cancers harbour mutations promoting activation of the Akt protein kinase. Because of this there are over 200 clinical trials listed on the NIH clinical trials website that have been i …more

Cullin-RING ligases (CRLs) are multi-subunit ubiquitin E3 enzymes, which ligate the small modifier ubiquitin to other cellular proteins. CRLs are modular complexes containing a core catalytic unit, which is combined with variable substrate-specific a …more

The MRC Protein Phosphorylation Unit and the SCottish Institute of ceLL Signalling (SCILLS) have merged into the MRC Protein Phosphorylation and Ubiquitylation Unit.

The new Unit will still retain the MRC-PPU brand name. Its scientists wil …more

Philip Cohen's research into the causes of inflammatory and autoimmune diseases has been boosted by the award of a grant of almost £1.7million from the Wellcome Trust to support his work over the next five years.



The grant …more

The MRC Protein Phosphorylation and Ubiquitylation Unit's flagship collaboration with pharmaceutical companies, termed Division of Signal Transduction Research (DSTT), is named by Health Science Scotland as their organisation of the month.

 …more