Much work in Dario Alessi's lab over the last 10 years has focused on understanding the function and regulation of the WNK1 and WNK4 family of protein kinases whose overexpression in humans causes Gordon's hypertension syndrome. Patients with thi …more

Helen Walden's lab studies the molecular mechanisms that control attachment of ubiquitin (a protein tag or signal) to its targets. Attachment requires the sequential action of 3 enzymes, E1, E2 and E3. E2s and E3s interact with each other to allow t …more

We warmly welcome Sonal Das, who joined the MRC-PPU on Monday 6th January.

Sonal will play a major role in helping to further develop the MRC-PPU. This will include organising our public engagement in science activities, taking charge of …more

Dr Miratul Muqit, Wellcome Trust Senior Research Fellow and Programme Leader in the MRC-PPU, has been awarded the prestigious 2013 Linacre Medal and Pri …more

Patrick Pedrioli has been awarded a £400,703 BBSRC responsive mode research grant to further his research into the function and regulation of tRNA post-transcriptional modifications.

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Well done to Eeva Sommer a PhD Student Dario Alessi's lab who successfully defended her PhD thesis on better understanding of the roles that SGK isoforms play in breast cancer. Her work has revealed that high levels of SGK isoforms and phosphorylati …more

We are delighted to announce that Greg Findlay has opened his first independent laboratory here at the MRC Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU).

Greg comes to us from the Samuel Lunenfeld Research Institute, Mount …more

Congratulations to Kei Sakamoto who is currently Head of Diabetes at the Néstle Institute of Health Sciences in Lausanne, Switzerland. Kei has been promoted to full professor at the nearby École Polytechnique Fé …more

Jeremy Nichols who is now the Director of Signal Transduction & LRRK2 Biology Program at the Parkinson's Institute and Clinical Center in Sunnyvale California has just received a Citation award for his paper entitled  …more

To aide worldwide research in protein phosphorylation and ubiquitylation, the MRC-PPU has launched a new website termed "MRC-PPU Reagents" in which researchers working in any academic laboratory can request any of our cDNA clones, antibodies or reco …more