Mitochondria are the powerhouses of the cell as they supply most of the fuel, known as ATP, that drives essential chemical reactions. They also perform many other important functions involved in metabolism, signalling, development and cell death. Giv …more
News
Parkinson's disease is an incurable neurodegenerative disorder and the MRC-PPU is at the frontline of research trying to understand the origins of this disease and developing new ideas on diagnosis and treatment.
On November 6th two PhD s …more
On November 6th two PhD s …more
Congratulations to MRC-PPU Principal Investigator (PI) Vicky Cowling, who has received an esteemed European Molecular Biology Organisation (EMBO) Young Investigator Programme (YIP) Prize. Every year EMBO go to great efforts to scour Europe, Israe …more
A group of postdocs and PhD students from the MRC-PPU, Frances Rose-Schumacher, Michael Munson, Sam Strickson, Catherine Rodger, Yosua Kristariyanto, George Allen, Nicola Phillips, Anna Kelner, Flora Keppie and Owen Conway, aided by MRC Communication …more
NUAK1 and NUAK2 are members of the AMPK family of protein kinase that are activated by the LKB1 tumour suppressor kinase. Recent work suggests they play important roles in regulating key biological processes including Myc driven tumourigenesis, senes …more
Congratulations to Manman Guo of the Trost lab who was awarded a prize at the College of Life Sciences 2nd Year PhD student poster competition on Friday 19th October 2013. Manman presented a poster entitled 'Characterization of phagosomal proteo …more
The University of Dundee's award-winning Division of Signal Transduction Therapy (DSTT) has this week celebrated the 50th meeting of the collaboration, which brings scientists at the University together with the world's biggest pharmaceutical com …more
RING-in-between-RING (RBR) enzymes are a distinct class of E3 ubiquitin ligases possessing a cluster of three zinc-binding domains that cooperate to catalyze ubiquitin transfer. The best known members of this group are PARKIN and HOIP, defects in whi …more
We are delighted to announce that Helen Walden and her PhD student Mark Frost have joined the MRC Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU). Helen has relocated her laboratory from the CRUK London Research Institute at Lincoln's I …more
