Much research in the MRC-PPU has focused on understanding the regulation and function of two related protein kinases termed NUAK1 and NUAK2 that are activated by the LKB1 tumor suppressor. LKB1 phosphorylates these enzymes at their T-loop residues st …more

Scientists and support staff from the MRC PPU recently enjoyed a visit with a P3 class at Forthill Primary for a fun morning of hands on experiments with a Superhero theme.

Laura  …more

Dr Kris Clark has been awarded a prestigious fellowship from Arthritis Research UK that will support his groundbreaking work developing new treatments for inflammatory arthritis over the next five yea …more

Philip Cohen has been elected a Corresponding Member of the Australian Academy of Science, one of only 27 scientists from around the world to hold the honour.

Philip was recognised for hi …more

Exactly 10 years ago mutations in a little studied kinase called PTEN-induced kinase 1 (PINK1) were discovered in patients with early-onset Parkinson's disease [Ref 1]. PINK1 is uniq …more

Many congratulation to Axel Knebel who has just received the CLS Innovator of the Year Prize for the development of a novel affinity purification tag termed the 'Dac-tag'.



Axel, runs the MRC-PPU Protein Production and Assay D …more

Recently, Newport primary school hosted a science week for its pupils (March 17th to the 21st). The pupils learned from a diverse team of experts representing many of the Centres at The University of Dundee including the MRC Protein Phosphorylation & …more

Mutations in the PINK1 and Parkin genes are associated with early-onset Parkinson's disease. PINK1 encodes a mitochondrial-localised protein kinase whilst Parkin encodes a RING-IBR-RING E3 ubiquitin ligase. In 2012 a former PhD student of Miratul Muq …more

Congratulations to Xu Huang who worked as a postdoc in Dario Alessi's lab (November 2004-May 2008) who has just been appointed to a group leader position at  …more

Many congratulations to MRC-PPU PI Helen Walden who has been awarded the prestigious Colworth Medal.

The Colworth Medal is sponsored by Unilever and presented by t …more