Cambridge & MRC-PPU | Visiting Clinical Scholar Awards



ubiquitinTwo Visiting Clinical Scholarships are available to early career clinical academic researchers based at the University of Cambridge (ACF, ACL, PhD, Clinician Scientist/Postdoctoral) to spend between 1 and 3 months undertaking research at the MRC Protein Phosphorylation & Ubiquitylation Unit (MRC-PPU) at the University of Dundee, one of Europe’s leading life sciences research institutes. The Unit has 12 internationally recognised research groups focused on unravelling the role of protein phosphorylation and ubiquitylation pathways in human diseases.

Visiting Clinical Scholars to the MRC-PPU will receive cutting edge training in mechanistic analysis of signalling pathways in a disease area relevant to their primary research project and interests. Areas of expertise in the Unit include neurodegeneration, cancer and inflammation but other fields of medical research relating to signalling pathways could also be explored. The MRC-PPU has a strong track record in deciphering the regulation of poorly studied signalling components that emerge from genetic analysis of human disease.

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The Visiting Clinical Scholarship will cover the cost of all travel to and from Dundee; accommodation; laboratory bench costs and consumables. Additional funds are available for successful applicants to visit the MRC-PPU to meet with prospective host PIs prior to starting their projects. There are direct flights from London Stansted to Dundee.

Application

Applications consisting of a current CV and cover letter should be sent to cato@medschl.cam.ac.uk. Candidates should express a preference for a host lab in the application. Participating labs are listed below.

The schedule for applications is as follows:

  • Applications open - November 21st 2018
  • Closing date for applications - 14th December 2018
  • Shortlist interviews - January 2019 (week beginning 21st - 25th)
  • Award available to be taken up any time after - March 2019

This Scholarship scheme is coordinated by Professor Brian Huntly, Director of CATO (Cambridge) and Dr. Miratul Muqit, a Wellcome Senior Clinical Fellow at the MRC-PPU.

For informal enquiries, please email Professor Brian Huntly or Dr Miratul Muqit.

Candidates wishing to discuss their research group preference should contact Prof. Dario Alessi (MRC PPU Director) or Dr. Miratul Muqit.

Disease Themes

Below are the research themes for each lab at the MRC PPU categorised by disease/therapy:

Neurodegeneration

Dario Alessi, Miratul Muqit, Ian Ganley, Yogesh Kulathu, Gopal Sapkota, Satpal Virdee, Adrien Rousseu

Cancer

John Rouse, Karim Labib, Gopal Sapkota, Dario Alessi

Inflammation

Philip Cohen, Mahima Swamy, Yogesh Kulathu

Stem Cell/Regenerative Medicine

Greg Findlay

Metabolic Medicine

Ian Ganley, Philip Cohen

Cardiovascular Medicine

Dario Alessi, Ian Ganley

Research Image LRRK2 Pathway and Parkinson’s DiseaseDario Alessi
Philip Research Picture The role protein phosphorylation and ubiquitylation in human health and diseasePhilip Cohen
Rouse lab research image Cell responses to DNA damage in health and human diseaseJohn Rouse
Muqit Research Image PINK1 kinase signalling networks in Parkinson's diseaseMiratul Muqit
Ganley research image Molecular analysis of autophagyIan Ganley
Virdee Research Image Molecular mechanisms of E3 ligases in disease pathwaysSatpal Virdee
Sapkota Research Image Understanding mechanisms of reversible phosphorylation and ubiquitylation in cell signalling and disease.Gopal Sapkota
Findlay Research Image How Does Dysregulated Signal Transduction Cause Intellectual Disability?Greg Findlay
Kulathu Research image Ubiquitin signalling mechanismsYogesh Kulathu
Labib Research Image Chromosome replication and genome integrityKarim Labib
Swamy Research Image Immune interactions at the intestinal epitheliumMahima Swamy
Rousseau Research image Signalling pathways controlling proteasome homeostasisAdrien Rousseau
Parkinson’s diseaseEsther Sammler
Mechanism for CRISPR perturbation Understanding the fundamental pathway, endoplasmic reticulum-specific autophagyJin Rui (Amos) Liang
Disease modelling of PIK3CA mutations, quantitative biology, pharmacologyRalitsa Madsen
Organoid development Technologies ResearchPaul Davies
Solving the black box of ALS involves studying proximal molecular mechanisms Unravelling the role of cell signalling in our molecular mechanistic understanding of amyotrophic lateral sclerosis/motor neuron diseaseArpan Mehta