Our lab focuses on developing technologies and approaches to solve challenging issues in research. We work in close collaboration with the pharmaceutical industry on a range of current medical challenges such as heart and lung disease, chronic kidney disease and neurodegenerative disorders. We are especially interested in the application of organoid technologies to generate novel and physiologically relevant models. Using these models, we are able to study pathways and evaluate potential therapeutics on a vast but highly reproducible scale.

We also undertake signalling pathway analysis using a variety of proteomic approaches and assay development to assist our Units researchers as well as our pharmaceutical partners. We are strong advocate of open science and make all of our technologies and reagents ads widely available as possible via our world renowned MRC Reagents and Services https://mrcppureagents.dundee.ac.uk.

Paul Leads on several open science projects, including the Influenza Toolkit (https://www.influenza.bio), and Covid Toolkit (https://mrcppu-covid.bio) in collaboration with CVR Glasgow.