Lipids have a role in virtually all biological processes, acting as structural elements, scaffolds and signaling molecules, but they are still largely under-represented in known biological networks. Here we describe a liposome microarray-based assay (LiMA), a method that measures protein recruitment to membranes in a quantitative, automated, multiplexed and high-throughput manner.
Author(s):
Saliba, A. E., Vonkova, I., Ceschia, S., Findlay, G. M., Maeda, K., Tischer, C., Deghou, S., van Noort, V., Bork, P., Pawson, T., Ellenberg, J., Gavin, A. C.
PubMed:
24270602
Citation:
Saliba, A. E., Vonkova, I., Ceschia, S., Findlay, G. M., Maeda, K., Tischer, C., Deghou, S., van Noort, V., Bork, P., Pawson, T., Ellenberg, J., Gavin, A. C.
Saliba, A. E., Vonkova, I., Ceschia, S., Findlay, G. M., Maeda, K., Tischer, C., Deghou, S., van Noort, V., Bork, P., Pawson, T., Ellenberg, J., Gavin, A. C.
Nat Methods
2014
11
47-50
PMID: 24270602