Research | Publications

Year

MAP kinase kinase from rabbit skeletal muscle. A novel dual specificity enzyme showing homology to yeast protein kinases involved in pheromone-dependent signal transduction

Nakielny, S., Campbell, D. G., Cohen, P.

Principal Investigator(s):
Philip Cohen
1992
PubMed

Ser Thr-Specific Protein Phosphatases Are Required for Both Catalytic Steps of Premessenger-Rna Splicing

Mermoud, J. E., Cohen, P., Lamond, A. I.

Principal Investigator(s):
Philip Cohen
1992

Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity

Liu, J., Albers, M. W., Wandless, T. J., Luan, S., Alberg, D. G., Belshaw, P. J., Cohen, P., MacKintosh, C., Klee, C. B., Schreiber, S. L.

Principal Investigator(s):
Philip Cohen
1992
PubMed

Activation of the Map Kinase Pathway by the Protein-Kinase Raf

Howe, L. R., Leevers, S. J., Gomez, N., Nakielny, S., Cohen, P., Marshall, C. J.

Principal Investigator(s):
Philip Cohen
1992

Arachidonic acid inhibits myosin light chain phosphatase and sensitizes smooth muscle to calcium

Gong, M. C., Fuglsang, A., Alessi, D., Kobayashi, S., Cohen, P., Somlyo, A. V., Somlyo, A. P.

Principal Investigator(s):
Dario Alessi, Philip Cohen
1992
PubMed

Myosin Light Chain Phosphatase-Activities and the Effects of Phosphatase Inhibitors in Tonic and Phasic Smooth-Muscle

Gong, M. C., Cohen, P., Kitazawa, T., Ikebe, M., Masuo, M., Somlyo, A. P., Somlyo, A. V.

Principal Investigator(s):
Philip Cohen
1992

Identification of a MAP kinase kinase kinase in phaeochromocytoma (PC12) cells

Gomez, N., Traverse, S., Cohen, P.

Principal Investigator(s):
Philip Cohen
1992
PubMed

P42 Map Kinase Phosphorylation Sites in Microtubule-Associated Protein Tau Are Dephosphorylated by Protein Phosphatase-2a1 - Implications for Alzheimers-Disease

Goedert, M., Cohen, E. S., Jakes, R., Cohen, P.

Principal Investigator(s):
Philip Cohen
1992

A myofibrillar protein phosphatase from rabbit skeletal muscle contains the beta isoform of protein phosphatase-1 complexed to a regulatory subunit which greatly enhances the dephosphorylation of myosin

Dent, P., MacDougall, L. K., MacKintosh, C., Campbell, D. G., Cohen, P.

Principal Investigator(s):
Philip Cohen
1992
PubMed

Characterization of the major phosphofructokinase-dephosphorylating protein phosphatases from Ascaris suum muscle

Daum, G., Schmid, B., MacKintosh, C., Cohen, P., Hofer, H. W.

Principal Investigator(s):
Philip Cohen
1992
PubMed

Dissection of the protein kinase cascades involved in insulin and nerve growth factor action

Cohen, P., Campbell, D. G., Dent, P., Gomez, N., Lavoinne, A., Nakielny, S., Stokoe, D., Sutherland, C., Traverse, S.

Principal Investigator(s):
Philip Cohen
1992
PubMed

Signal integration at the level of protein kinases, protein phosphatases and their substrates

Cohen, P.

Principal Investigator(s):
Philip Cohen
1992
PubMed

The Amino-Acid-Sequence of a Mammalian Map Kinase Kinase

Ashworth, A., Nakielny, S., Cohen, P., Marshall, C.

Principal Investigator(s):
Philip Cohen
1992

The control of protein phosphatase-1 by targetting subunits. The major myosin phosphatase in avian smooth muscle is a novel form of protein phosphatase-1

Alessi, D., MacDougall, L. K., Sola, M. M., Ikebe, M., Cohen, P.

Principal Investigator(s):
Dario Alessi, Philip Cohen
1992
PubMed

Isolation and analysis of the fission yeast gene encoding polymerase delta accessory protein PCNA

Waseem, N. H., Labib, K., Nurse, P., Lane, D. P.

Principal Investigator(s):
Karim Labib
1992
PubMed

Synthesis and properties of a conformationally restricted spin-labeled analog of ATP and its interaction with myosin and skeletal muscle

Alessi, D. R., Corrie, J. E., Fajer, P. G., Ferenczi, M. A., Thomas, D. D., Trayer, I. P., Trentham, D. R.

Principal Investigator(s):
Dario Alessi
1992
PubMed

Insulin action and responses - the biochemistry of post-receptor events

Hardie, D.G., Cohen, P.

Principal Investigator(s):
Philip Cohen
1991
PubMed

p34cdc2 phosphorylation sites in histone H1 are dephosphorylated by protein phosphatase 2A1

Sola, M. M., Langan, T., Cohen, P.

Principal Investigator(s):
Philip Cohen
1991
PubMed

The discovery of glycogenin and the priming mechanism for glycogen biogenesis

Smythe, C., Cohen, P.

Principal Investigator(s):
Philip Cohen
1991
PubMed

The molecular mechanism by which adrenalin inhibits glycogen synthesis

Nakielny, S., Campbell, D. G., Cohen, P.

Principal Investigator(s):
Philip Cohen
1991
PubMed