Research | Publications

Year

THE ALPHA-ISOFORM OF GLYCOGEN-SYNTHASE KINASE-3 FROM RABBIT SKELETAL-MUSCLE IS INACTIVATED BY P70 S6 KINASE OR MAP KINASE-ACTIVATED PROTEIN KINASE-1 IN-VITRO

Sutherland, C., Cohen, P.

Principal Investigator(s):
Philip Cohen
1994

Oxidative stress and heat shock induce the expression of the human CL100 gene, which encodes a dual specificity (Thr/Tyr) MAP kinase phosphatase

Sneddon, A. A., Lewis, T. A. , Smythe, C. , Alessi, D. R., Keyse, S. M.

Principal Investigator(s):
Dario Alessi
1994

The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells

Saito, Y., Vandenheede, J. R., Cohen, P.

Principal Investigator(s):
Philip Cohen
1994
PubMed

THE MECHANISM BY WHICH EPIDERMAL GROWTH-FACTOR INHIBITS GLYCOGEN-SYNTHASE KINASE 3 IN A431 CELLS

Saito, Y., Vandenheede, J. R., Cohen, P.

Principal Investigator(s):
Philip Cohen
1994

The threonine residues in MAP kinase kinase 1 phosphorylated by MAP kinase in vitro are also phosphorylated in nerve growth factor-stimulated rat phaeochromocytoma (PC12) cells

Saito, Y., Gomez, N., Campbell, D. G., Ashworth, A., Marshall, C. J., Cohen, P.

Principal Investigator(s):
Philip Cohen
1994
PubMed

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

Rouse, J., Cohen, P., Trigon, S., Morange, M., Alonso-Llamazares, A., Zamanillo, D., Hunt, T., Nebreda, A. R.

Principal Investigator(s):
Philip Cohen, John Rouse
1994
PubMed

A NOVEL KINASE CASCADE TRIGGERED BY STRESS AND HEAT-SHOCK THAT STIMULATES MAPKAP KINASE-2 AND PHOSPHORYLATION OF THE SMALL HEAT-SHOCK PROTEINS

Rouse, J., Cohen, P., Trigon, S., Morange, M., Alonsollamazares, A., Zamanillo, D., Hunt, T., Nebreda, A. R.

Principal Investigator(s):
Philip Cohen, John Rouse
1994

Epitope Mapping of Monoclonal-Antibodies to the Paired Helical Filaments of Alzheimers-Disease - Identification of Phosphorylation Sites in Tau-Protein

Goedert, M., Jakes, R., Crowther, R. A., Cohen, P., Vanmechelen, E., Vandermeeren, M., Cras, P.

Principal Investigator(s):
Philip Cohen
1994

CELLS OF TH2 CYTOKINE PHENOTYPE PREVENT LPS-INDUCED LETHALITY DURING MURINE GRAFT-VERSUS-HOST REACTION - REGULATION OF CYTOKINES AND CD8+ LYMPHOID ENGRAFTMENT

Fowler, D. H., Kurasawa, K., Husebekk, A., Cohen, P. A., Gress, R. E.

Principal Investigator(s):
Philip Cohen
1994

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kin

Cross, D. A., Alessi, D. R., Vandenheede, J. R., McDowell, H. E., Hundal, H. S., Cohen, P.

Principal Investigator(s):
Dario Alessi, Philip Cohen
1994
PubMed

EXPRESSION OF STEM-CELL FACTOR AND C-KIT IN HUMAN NEUROBLASTOMA

Cohen, P. S., Chan, J. P., Lipkunskaya, M., Biedler, J. L., Seeger, R. C.

Principal Investigator(s):
Philip Cohen
1994

MURINE EPIDERMAL LANGERHANS CELLS AND SPLENIC DENDRITIC CELLS PRESENT TUMOR-ASSOCIATED ANTIGENS TO PRIMED T-CELLS

Cohen, P. J., Cohen, P. A., Rosenberg, S. A., Katz, S. I., Mule, J. J.

Principal Investigator(s):
Philip Cohen
1994

THE IGF AXIS IN THE PROSTATE

Cohen, P., Peehl, D. M., Rosenfeld, R. G.

Principal Investigator(s):
Philip Cohen
1994

BIOLOGICAL EFFECTS OF PROSTATE-SPECIFIC ANTIGEN AS AN INSULIN-LIKE GROWTH-FACTOR BINDING PROTEIN-3 PROTEASE

Cohen, P., Peehl, D. M., Graves, H. C. B., Rosenfeld, R. G.

Principal Investigator(s):
Philip Cohen
1994

INSULIN-LIKE GROWTH-FACTOR AXIS ABNORMALITIES IN PROSTATIC STROMAL CELLS FROM PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA

Cohen, P., Peehl, D. M., Baker, B., Liu, F., Hintz, R. L., Rosenfeld, R. G.

Principal Investigator(s):
Philip Cohen
1994

The discovery of protein phosphatases: from chaos and confusion to an understanding of their role in cell regulation and human disease

Cohen, P.

Principal Investigator(s):
Philip Cohen
1994
PubMed

Molecular cloning of cDNA encoding the 110 kDa and 21 kDa regulatory subunits of smooth muscle protein phosphatase 1M

Chen, Y. H., Chen, M. X., Alessi, D. R., Campbell, D. G., Shanahan, C., Cohen, P., Cohen, P. T. W.

Principal Investigator(s):
Philip Cohen, Dario Alessi
1994
PubMed

Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1

Alessi, D. R., Saito, Y., Campbell, D. G., Cohen, P., Sithanandam, G., Rapp, U., Ashworth, A., Marshall, C. J., Cowley, S.

Principal Investigator(s):
Dario Alessi, Philip Cohen
1994
PubMed

Regulation of the cell cycle timing of Start in fission yeast by the rum1+ gene

Moreno, S., Labib, K., Correa, J., Nurse, P.

Principal Investigator(s):
Karim Labib
1994
PubMed

Specific association of activated MAP kinase kinase kinase (Raf) with the plasma membranes of ras-transformed retinal cells

Traverse, S., Cohen, P., Paterson, H., Marshall, C., Rapp, U., Grand, R. J.

Principal Investigator(s):
Philip Cohen
1993
PubMed