Research | Publications

Year

Phosphotyrosine residues in the nerve-growth-factor receptor (Trk-A). Their role in the activation of inositolphospholipid metabolism and protein kinase cascades in phaeochromocytoma (PC12) cells

Baxter, R. M., Cohen, P., Obermeier, A., Ullrich, A., Downes, C. P., Doza, Y. N.

Principal Investigator(s):
Philip Cohen
1995
PubMed

Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines

Alessi, D. R., Gomez, N., Moorhead, G., Lewis, T., Keyse, S. M., Cohen, P.

Principal Investigator(s):
Dario Alessi, Philip Cohen
1995
PubMed

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

Alessi, D. R., Cuenda, A., Cohen, P., Dudley, D. T., Saltiel, A. R.

Principal Investigator(s):
Dario Alessi, Philip Cohen
1995
PubMed

Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf

Alessi, D. R., Cohen, P., Ashworth, A., Cowley, S., Leevers, S. J., Marshall, C. J.

Principal Investigator(s):
Dario Alessi, Philip Cohen
1995
PubMed

Interaction of cdc2 and rum1 regulates Start and S-phase in fission yeast

Labib, K., Moreno, S., Nurse, P.

Principal Investigator(s):
Karim Labib
1995
PubMed

Dominant mutants identify new roles for p34cdc2 in mitosis

Labib, K., Craven, R. A., Crawford, K., Nurse, P.

Principal Investigator(s):
Karim Labib
1995
PubMed

EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

Traverse, S., Seedorf, K., Paterson, H., Marshall, C. J., Cohen, P., Ullrich, A.

Principal Investigator(s):
Philip Cohen
1994
PubMed

Identification of a latent MAP kinase kinase kinase in PC12 cells as B-raf

Traverse, S., Cohen, P.

Principal Investigator(s):
Philip Cohen
1994
PubMed

The alpha-isoform of glycogen synthase kinase-3 from rabbit skeletal muscle is inactivated by p70 S6 kinase or MAP kinase-activated protein kinase-1 in vitro

Sutherland, C., Cohen, P.

Principal Investigator(s):
Philip Cohen
1994
PubMed

THE ALPHA-ISOFORM OF GLYCOGEN-SYNTHASE KINASE-3 FROM RABBIT SKELETAL-MUSCLE IS INACTIVATED BY P70 S6 KINASE OR MAP KINASE-ACTIVATED PROTEIN KINASE-1 IN-VITRO

Sutherland, C., Cohen, P.

Principal Investigator(s):
Philip Cohen
1994

Oxidative stress and heat shock induce the expression of the human CL100 gene, which encodes a dual specificity (Thr/Tyr) MAP kinase phosphatase

Sneddon, A. A., Lewis, T. A. , Smythe, C. , Alessi, D. R., Keyse, S. M.

Principal Investigator(s):
Dario Alessi
1994

The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells

Saito, Y., Vandenheede, J. R., Cohen, P.

Principal Investigator(s):
Philip Cohen
1994
PubMed

THE MECHANISM BY WHICH EPIDERMAL GROWTH-FACTOR INHIBITS GLYCOGEN-SYNTHASE KINASE 3 IN A431 CELLS

Saito, Y., Vandenheede, J. R., Cohen, P.

Principal Investigator(s):
Philip Cohen
1994

The threonine residues in MAP kinase kinase 1 phosphorylated by MAP kinase in vitro are also phosphorylated in nerve growth factor-stimulated rat phaeochromocytoma (PC12) cells

Saito, Y., Gomez, N., Campbell, D. G., Ashworth, A., Marshall, C. J., Cohen, P.

Principal Investigator(s):
Philip Cohen
1994
PubMed

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

Rouse, J., Cohen, P., Trigon, S., Morange, M., Alonso-Llamazares, A., Zamanillo, D., Hunt, T., Nebreda, A. R.

Principal Investigator(s):
Philip Cohen, John Rouse
1994
PubMed

A NOVEL KINASE CASCADE TRIGGERED BY STRESS AND HEAT-SHOCK THAT STIMULATES MAPKAP KINASE-2 AND PHOSPHORYLATION OF THE SMALL HEAT-SHOCK PROTEINS

Rouse, J., Cohen, P., Trigon, S., Morange, M., Alonsollamazares, A., Zamanillo, D., Hunt, T., Nebreda, A. R.

Principal Investigator(s):
Philip Cohen, John Rouse
1994

Epitope Mapping of Monoclonal-Antibodies to the Paired Helical Filaments of Alzheimers-Disease - Identification of Phosphorylation Sites in Tau-Protein

Goedert, M., Jakes, R., Crowther, R. A., Cohen, P., Vanmechelen, E., Vandermeeren, M., Cras, P.

Principal Investigator(s):
Philip Cohen
1994

CELLS OF TH2 CYTOKINE PHENOTYPE PREVENT LPS-INDUCED LETHALITY DURING MURINE GRAFT-VERSUS-HOST REACTION - REGULATION OF CYTOKINES AND CD8+ LYMPHOID ENGRAFTMENT

Fowler, D. H., Kurasawa, K., Husebekk, A., Cohen, P. A., Gress, R. E.

Principal Investigator(s):
Philip Cohen
1994

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kin

Cross, D. A., Alessi, D. R., Vandenheede, J. R., McDowell, H. E., Hundal, H. S., Cohen, P.

Principal Investigator(s):
Dario Alessi, Philip Cohen
1994
PubMed

EXPRESSION OF STEM-CELL FACTOR AND C-KIT IN HUMAN NEUROBLASTOMA

Cohen, P. S., Chan, J. P., Lipkunskaya, M., Biedler, J. L., Seeger, R. C.

Principal Investigator(s):
Philip Cohen
1994