The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 60 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.

We are recruiting a highly motivated Technician to join the laboratory of Dr Kirby Swatek in the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit at the University of Dundee.

The Swatek lab aims to understand the roles of ubiquitin and ubiquitin-like modifications in the antiviral response. These modifications have emerged as critical regulators of the signalling pathways that sense and respond to invading pathogens. The ubiquitin-like protein, ISG15, is highly upregulated in response to viral infection and labels thousands of proteinsto help shape the host defenceresponse. However, the mechanisms underlying ISG15's contribution to antiviral immunity remain largely unknown. Therefore, studying ISG15 signalling has the potential to unlock exciting new areas of biology.

The successful applicant will assist in the lab's day-to-day operations, which will include maintaining cell lines, insect and mammalian protein expression, and routine biochemical and biophysical assays.

Furthermore, the post-holder will help maintain supplies, databases, and critical equipment in the laboratory.

This post is fixed term until no later than 30 March 2024.

Your priorities will include:

• Cloning, expression, and purification of proteins (~50%)
• Maintaining insect and mammalian cell lines (~20%)
• Assisting other lab members (~lo%)
• Documenting experiments and generating standard operating procedures 10%)
• Maintaining laboratory supplies, databases, and equipment (~5%)
• Biochemical and biophysical assays(~5%)

Who we're looking for:

• Applicant must have a Bachelor of Science degree
• Experience in standard molecular and biochemical techniques
• Experience in routine tissue culture work
• The ability to work in a small team of enthusiastic scientists
• Excellent communication and organisational skills

We are one of the UK's leading universities - internationally recognised for our expertise across a range of disciplines and research breakthroughs in multiple areas, including science, medicine and engineering, amongst many others. Conveniently located on the banks of River Tay, our main city-centre campus is at the heart of Dundee - an up-and-coming, friendly, compact and affordable city with a rich heritage in design and technology. Just a short walk from the V&A Museum of Design Dundee, we're close to both the train and bus stations. We also have campuses at Ninewells Hospital and in Kirkcaldy which are easily accessible via local transport links.

Please contact Dr Kirby Swatekfor informal enquiries(kswatek001@dundee.ac.uk).

The diversity of our staff and students helps to make the University of Dundee one of the top universities in the UK. Family friendly policies, staff support networks for BME and LGBT staff, membership of Athena Swan and Stonewall, as well a full range of disability services, create an enjoyable and inclusive place to work.