Gerardo Gamba (Universidad Nacional Autonoma México), one of the founders of the ion cotransporter field of research, visited the MRC Unit with two of his colleagues - Diana Pacheco-Alvarez and Paola de los Heros - to discuss research on how the WNK and SPAK signalling pathways regulate these enzymes. This lead to very stimulating discussions as well as a very nice dinner in the Lands of Loyal, which Unit members Fatema Rafiqi, Ciaran Richardson, Lali Guisado and Jacob Thastrup, working on this pathway, attended. We hope this visit will lead to interactions between our groups and a greater molecular understanding on the mechanisms by which the WNK signalling pathway regulates blood pressure.