Members of the MRC PPU recently took part in an exciting event on Parkinson’s and Art organized by Werner Remmele, Secretary of the Dundee Research Interest Group (DRIG), a partnership formed with the University of Dundee and Parkinson’s patients interested in research.
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The serum- and glucocorticoid-regulated kinase-3 (SGK3) contribute resistance to cancer therapies targeting the PI3K pathway. Recent work has shown that the SGK3 isoform is upregulated in breast cancer cells treated with PI3K or Akt inhibitors and recruited and activated at endosomes, through its phox homology domain binding to PtdIns(3)P.
…moreMRC PPU scientists contributed to an interactive art exhibition entitled ‘Misprints’ by artist Daksha Patel held at the Dundee Contemporary Arts (DCA) on October 8th 2019 during
…moreOn October 1st 1969 Philip Cohen became a postdoc in Edmond Fischer’s lab at the University of Washington, Seattle, USA and started his research on protein phosphorylation.
…moreOn Sunday, 29 September 2019, researchers and friends from the MRC PPU including Professor Dario Alessi ran the Glasgow 10K race as part of Marc van Grieken’s “Shaky Team from Shaky Toun” to raise awareness and money for research into Parkinson’s disease.
…moreTheresita Joseph, who was jointly supervised by Miratul Muqit and Dario Alessi, has successfully defended her Masters by Research Degree (MSc) studying Parkinson’s signalling pathways in human and mouse immune cells.
…moreTheresita Joseph, who was jointly supervised by Miratul Muqit and Dario Alessi, has successfully defended her Masters by Research Degree (MSc) studying Parkinson’s signalling pathways in human and mouse immune cells.
…moreHannah Tovell, a PhD student in Dario Alessi's lab, working in collaboration with Claire Crafter (AstraZeneca) and Alessio Ciulli and Andrea Testa in the Ciulli lab, have elaborated a compound that we have termed SGK3-PROTAC1 that induces selective degradation of SGK3 protein kinase.
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On 21st August, MRC PPU proteomic research manager, Dr. Houjiang Zhou, delivered a distinguished alumni lecturer in DICP, China.
…moreThe concerted action of several protein kinases helps orchestrate the error-free transition through a mammalian cell division cycle.
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