MRC Protein Phosphorylation and Ubiquitylation Unit
with
A postdoctoral research position is available in Dr. Greg Findlay’s laboratory at the MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, to investigate functions of protein kinases in Embryonic Stem (ES) cell biology.
The Findlay lab employs cutting-edge technologies to unravel ES cell signalling networks (Williams et al, Cell Rep 2016, Fernandez-Alonso et al, EMBO Rep 2017; Bustos et al, Cell Rep 2018), culminating in our recent discovery of the ERK5 pathway as an exciting new regulator of ES cell pluripotency. In order to uncover mechanisms by which ERK5 controls ES cell biology, the project will deploy global proteomic and phosphoproteomic profiling. Novel ERK5 substrates and transcriptional networks will be characterised using biochemical and cell biology approaches. A further aim is to investigate functions of ERK5 in patient-derived human induced pluripotent stem cell maintenance and lineage-specific differentiation.
We invite applications from talented and motivated individuals who were recently awarded or are nearing the completion of a PhD in Cell and Molecular Biology or Biochemistry. An interest in protein phosphorylation, signal transduction and/or stem cell biology is desirable. The candidate should possess an outstanding academic track record, enthusiasm for research and excellent communication skills.
For informal enquiries please contact Greg Findlay (g.m.findlay@dundee.ac.uk). Closing date 7th January 2019.
This research will be undertaken in the MRC Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU), based in the School of Life Sciences at the University of Dundee. The MRC-PPU is one of the world’s leading centres studying the role of protein phosphorylation in health and disease. The successful applicant will have access to state-of-the-art tools to dissect signalling networks, and opportunity for interaction with major Pharmaceutical companies that support the MRC-PPU via the Division of Signal Transduction Therapy. The Findlay lab is also affiliated with the Division of Cell and Developmental Biology, which contains world leading experts in stem cell research.
Situated on a beautiful estuary close to some of Scotland’s most spectacular scenery, Dundee offers affordable living and a perfect blend of coast and countryside. The city is also developing into a major cultural hub, culminating in the recent opening of the iconic V&A Dundee Art Gallery.
The position will be for 3 years in the first instance. Salary is University of Dundee Grade 7 salary scale (£32,236 - £39,609), dependent upon PhD award. If you have not yet been awarded a PhD, initial appointment will be made as a Research Assistant on the Training Grade 7 salary scale (£31,302).
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To apply on-line please visit: www.dundee.ac.uk/jobs. If you are unable to apply on-line please contact Human Resources on (01382) 386209 (answering machine) for an application pack. Please quote reference number
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