Lab Member | Francois Singh

Postdoctoral Researcher

Francois Singh Portrait
Current Lab Member
- Now )

I joined the lab in February 2017 as a Postdoctoral Research Assistant. My project aims to determine the physiological role of LRRK2 in autophagosomal trafficking to the lysosome in vivo.

Before joining the lab, I studied Life Sciences at the University of Strasbourg and realised my PhD in collaboration between the Clinical Pharmacology and Toxicology lab of Professor Stephan Krähenbühl at the University of Basel (Switzerland) and the EA3072: Mitochondria, Oxidative Stress and Muscular Protection Lab of Professor Bernard Geny at the University of Strasbourg (France). During my PhD, I investigated the role of mitochondrial adaptations in statin-induced myotoxicity, focusing on the opposite effect of statins in glycolytic muscles (repression of mitochondrial biogenesis and triggering of apoptotic pathways) and in oxidative muscles (activation of mitochondrial biogenesis and enhanced mitochondrial function).

Country of Origin: France