Lambert Montava Garriga, a PhD student in the Ganley Lab at the MRC PPU, was awarded the first-place poster prize at the Biochemical Society’s 83rd Harden Conference: Autophagy – from Molecules to Disease.

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Ever wondered what the inside of a lab looks like? We’ll be hosting an open day on Saturday 16 June so please join us to explore the world of medical research.

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Sven Lange, a PhD student in the MRC PPU has won The FEBS Journal Poster Prize at "Pseudoenzymes 2018: from molecular mechanism to cell biology" which was held on the island of Sardinia from May 16-19 2018.

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The CK1 family of serine/threonine protein kinases were one of the first kinases to be discovered some 50 years ago, principally because of their incessant ability to phosphorylate the milk protein casein in the test tube.

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David Campbell, head of the MRC PPU’s Mass Spectrometry Facility, is retiring 34 years after joining Philip Cohen’s lab as a postdoc in 1984. …more

Missense mutations that induce hyper-activation of the LRRK2 protein kinase cause autosomal dominant Parkinson’s disease. LRRK2 phosphorylates a subgroup of Rab GTPases within their Switch-II effector binding motifs that impacts on their ability to associate with critical effectors.

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Following his recent Senior Investigator Award of £2.3million from the Wellcome Trust, Philip Cohen has now been awarded a new Programme Grant of £1.6 million from the Medical Research Council.

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New research by Greg Findlay’s group in the MRC PPU has made progress in understanding the fundamentals of intellectual disability, a developmental disorder thought to affect 1-2% of the world’s population.

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The Michael J. Fox Foundation for Parkinson’s Research (MJFF) has awarded MRC PPU Director Dario Alessi the 2018 MJFF Langston Award for “service and dedication to our shared goals of advancing Parkinson's understanding and therapeutic development”. For further information see here.

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Dr Virdee and colleagues in the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC PPU) have discovered a novel class of E3 ligase. The E3 ligase, MYCBP2, operates in a unique way, selectively transferring ubiquitin to non-lysine amino acids with selectivity for threonine.

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