Alban Ordureau, a graduate student working in Philip Cohen's laboratory, was awarded his PhD on May 23rd for a thesis entitled, "An investigation of the role of E3 ubiquitin ligases in regulating innate immunity".

The examination consisted …more

Scientists in the MRC Protein Phosphorylation Unit have discovered that a polyubiquitin-binding protein called ABIN1 plays a key role in preventing autoimmune disease and their findings were published  …more

The Arthur Research Group are going to walk Ben Nevis (Britain's highest mountain!) on Saturday 2nd July 2011 in aid of Arthritis Research UK. They have chosen this charity as much of their research relates to understanding how inflammation is re …more

Diabetes research run by Kei Sakamoto's group in the Unit has been boosted by the donation of £4,000 from the Dundee and District Diabetes UK Volunteer Group. The group raised money through a number of fundraising activities; hosting a bingo night, o …more

Recent studies have revealed that mutations within the Tau tubulin Kinase 2 (TTBK2) cause a serious autosomal dominant inherited movement disorder termed spinocerebellar ataxias type 11 (SCA11) [1, 2]. SCA11 is characterised by progressive cerebellar …more

Princess Anne, the Princess Royal, visited the MRC Protein Phosphorylation Unit on April 19 in her role as the President of Tenovus, a Scottish cancer charity. The Princess met John Rouse, one of the Unit's Programme Leaders, who was recently awa …more

Miratul Muqit, a Wellcome Intermediate Fellow working with Dario Alessi, has been appointed a Consultant Neurologist at Ninewells Hospital in Dundee. Miratul was the first clinician to be appointed to the MRC-PPU and now becomes the first to reach th …more

The PI 3-kinase-mTOR signalling pathway is activated in the majority of human tumours and there is great interest in assessing whether inhibitors of PI 3-kinase or mTOR kinase would have efficacy in treating cancers in which this pathway is over acti …more

A few years ago at the beginning of her PhD Laura Pearce identified novel components of the mTOR complex 2 (mTORC2) that she termed Protor-1 and Protor-2. Laura found that Protor isoforms interacted with the mTORC2 component Rictor. Protor-1 and Prot …more

Beatrice Filippi and Paola de los Heros MRC Unit postdocs working in Dario Alessi's lab have reevaluated the role of the MO25 scaffolding protein, that Jerome Boudeau - a previous postdoc now running a lab in Montpellier - discovered was a key compon …more