Protein phosphatase 2A (PP2A) is a highly abundant and essential Ser/Thr phosphatase that regulates a plethora of cellular processes. PP2A primarily operates as a holoenzyme complex, comprising one each of the scaffolding (A), regulatory (B) and catalytic (C) subunits. PPP2CA is the principal catalytic subunit of the PP2A holoenzyme complex.
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In a groundbreaking study, researchers from the MRC PPU, University of Dundee working in collaboration with researchers at University of Leeds have unveiled a critical new understanding of how cells control membrane protein synthesis.
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We are delighted that Gerta Hoxhaj, who was an MRCPPU PhD student in Carol MacKintosh's laboratory (2008-2012), has been awarded a $50,000, prestigious 2024 Vilcek Prize for Creative Promise in Biomedical Science. This prize recognizes young immigrant professionals in the US for outstanding achievements.
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We are delighted to announce that Dr Arpan Mehta, a neurologist specialising in Amyotrophic Lateral Sclerosis (ALS), a devastating disorder for which there are very limited treatments, will commence his research today at the MRC PPU.
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To facilitate the analysis of mass spectrometry-based proteomics data, MRCPPU researchers Toan Phung working closely with Raja Nirujogi have generated free-to-use interactive tools termed CURTAIN (https://curtain.proteo.info) and CURTAIN-PTM (https://curtainptm.proteo.info).
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Over 50 researchers, people with Parkinson’s, and carers came together at an Open Day on 6th February 2024 to discuss the latest Parkinson’s research in Dundee, tour different labs and facilities, and connect over lunch. …more
Tom Snelling a postdoctoral researcher in Philip Cohen’s lab has been awarded the Howard Elder Prize for a paper entitled “ALPK1 mutants causing ROSAH syndrome or Spiradenoma are activated by human nucleotide sugars”.
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Ricardo Moreno Ballesteros has emerged as the recipient of the University of Dundee, Innovator of the Year Business Award. Ricardo received his prize at the School of Life Sciences (SLS) Review of Year, attended by University of Dundee life science staff.
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Joshua Peter, a recently graduated PhD student from Yogesh Kulathu’s lab, has been awarded the 2023 Dundee Molecular and Cellular Biology Prize for his work on the poorly understood ubiquitin-like modifier, UFM1.
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Our ‘Exchanges: Inspiring Parkinson's Conversations’ project won the Brian Cox Award for Excellence in Public Engagement with Research (Best Project 2023) at the School of Life Sciences Review of the Year event on Wednesday 24th January. …more