In ground-breaking new work published in Molecular Cell, Yogesh Kulathu and colleagues report the discovery of a completely new family of Deubiquitinating enzymes (DUBs). …more
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On May 20th, Philip Cohen was awarded an honorary doctorate by the Universidad di Autonoma di Madrid. After receiving the award, Philip then gave a 30 minute talk about his career to an audien …more

Christophe Lachaud has won a Principal Investigator position from the Centre National de Recherche Scientifique (CNRS), the premier research funding agency in France. Each year, the CNRS elects a small number of rese …more

Our fifth alumni interview is with Kei Sakamoto, ex-MRC PPU postdoc (in Dario Alessi's group) and group leader, and now Head of Diabetes and Circadian Rhythms at Nestlé Institute of Heal …more

Miratul Muqit, a Wellcome Trust Senior Clinical Fellow in the MRC PPU, has been elected Fellow of the Royal College of Physicians. Founded in 1518, the Royal College of Physicians is England's oldest medical institution and …more

Our fourth alumni interview is with Mirela Delibegovic, ex-MRC PPU PhD student in Tricia Cohen's group. Click the MRC PPU Alumni Interview icon on the top of our website, or here to read the interview. …more

Our third alumni interview is with David Komander, ex-MRC PPU PhD student in Dario Alessi's group. Click the new MRC PPU Alumni Interview icon on the top of our website, or here to read the interview. …more
E3 ligases are one of the largest enzyme families and they confer substrate specificity in the ubiquitin conjugation process. E3 activity is often stringently regulated and aberrant activity is the hallmark of many diseases including neurodegeneratio …more