Scientists at the MRC Protein Phosphorylation and Ubiquitylation Unit have discovered that 'molecular scissors' that repair damaged and abnormal DNA are critical for keeping cancers at bay.



The laboratory of Professor John Rou …more

MRC PPU Lab Manager, Allison Bridges, today celebrates 15 years service having joined the Unit on February 1st, 2001 as support technician.

Presenting Allison with a bottle of 15-year old rum to mark the occasion, Unit Director Dario Ales …more

We want to capture some of the major achievements of students and postdocs who trained at the MRC Protein Phosphorylation and Ubiquitylation Unit (MRC PPU), and have created a new feature on our website the 'MRC PPU Alumni Interview'. These interview …more

There was a lot of excitement 11 years ago when it was discovered that autosomal dominant missense mutations within the gene encoding for a previously unstudied protein kinase termed LRRK2 (leucine-rich repeat protein kinase 2) predispose humans to d …more

We have completely overhauled the MRC Protein Phosphorylation and Ubiquitylation Unit (MRC PPU) reagents and services website which lists all of the MRC-PPU's, cDNA clones, antibodies and recombinant proteins that have been generated over the years i …more

Congratulations to Mirela Delibegovic, a PhD student in Tricia Cohen's laboratory from 1999 to 2003, on her recent promotion to Professor in the School of Biological Sciences, University of Aberdeen, UK! M …more

The MRC PPU is proud to announce that Dr. Yogesh Kulathu has been recognized yet again for his outstanding work by receiving a highly sought after  …more

Kashyap Patel, a former clinical PhD student in Kei Sakamoto's lab in the MRC PPU, has been awarded a highly competitive Wel …more

On 5 November, 2015 Sam Strickson, who has been supervised by Philip Cohen, has successfully defended his PhD. Over the past 4 years Sam has performed groundbreaking research into the role of the ubiquitin system in regulating the Interleukin 1 signa …more

Darren Cross who undertook is PhD training within the MRC-PPU working in Philip Cohen's laboratory (1993-1997) has played a major role in developing a new drug termed TAGRISSOââ€_¢ (AZD9291) that was recently approved (13 November 2015) by the US F …more