Research | Publications

Year

Traceless and site-specific ubiquitination of recombinant proteins

Virdee, S., Kapadnis, P. B., Elliott, T., Lang, K., Madrzak, J., Nguyen, D. P., Riechmann, L., Chin, J. W.

Principal Investigator(s):
Satpal Virdee
2011
PubMed

RUTBC1 Protein, a Rab9A Effector That Activates GTP Hydrolysis by Rab32 and Rab33B Proteins

Nottingham, R. M., Ganley, I. G., Barr, F. A., Lambright, D. G., Pfeffer, S. R.

Principal Investigator(s):
Ian Ganley
2011
PubMed

Hydrophobic, aromatic, and electrostatic interactions play a central role in amyloid fibril formation and stability

Marshall, K. E., Morris, K. L., Charlton, D., O'Reilly, N., Lewis, L., Walden, H., Serpell, L. C.

2011
PubMed

Surviving chromosome replication: the many roles of the S-phase checkpoint pathway

Labib, K., De Piccoli, G.

Principal Investigator(s):
Karim Labib
2011
PubMed

Building a double hexamer of DNA helicase at eukaryotic replication origins

Labib, K.

Principal Investigator(s):
Karim Labib
2011
PubMed

Structural analysis of human FANCL, the E3 ligase in the Fanconi anemia pathway

Hodson, C., Cole, A. R., Lewis, L. P., Miles, J. A., Purkiss, A., Walden, H.

2011
PubMed

Thapsigargin distinguishes membrane fusion in the late stages of endocytosis and autophagy

Ganley, I. G., Wong, P. M., Jiang, X.

Principal Investigator(s):
Ian Ganley
2011
PubMed

Distinct autophagosomal-lysosomal fusion mechanism revealed by thapsigargin-induced autophagy arrest

Ganley, I. G., Wong, P. M., Gammoh, N., Jiang, X.

Principal Investigator(s):
Ian Ganley
2011
PubMed

Autoregulation of Parkin activity through its ubiquitin-like domain

Chaugule, V. K., Burchell, L., Barber, K. R., Sidhu, A., Leslie, S. J., Shaw, G. S., Walden, H.

2011
PubMed

Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains

Akutsu, M., Ye, Y., Virdee, S., Chin, J. W., Komander, D.

Principal Investigator(s):
Satpal Virdee
2011
PubMed

Epithelial decision makers: in search of the 'epimmunome'

Swamy, M., Jamora, C., Havran, W., and Hayday, A.

Principal Investigator(s):
Mahima Swamy
2010
PubMed

Stoichiometry and intracellular fate of TRIM-containing TCR complexes

Swamy M, Siegers GM, Fiala GJ, Molnar E, Dopfer EP, Fisch P, Schraven B, Schamel WW.

Principal Investigator(s):
Mahima Swamy
2010
PubMed

The structure of FANCL, the catalytic subunit of the Fanconi Anemia core complex

Cole, AR., Lewis, LPC, Walden, H

2010
PubMed

New roles for the LKB1-NUAK pathway in controlling myosin phosphatase complexes and cell adhesion

Zagorska, A., Deak, M., Campbell, D. G., Banerjee, S., Hirano, M., Aizawa, S., Prescott, A. R., Alessi, D. R.

Principal Investigator(s):
Dario Alessi
2010
PubMed

PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR

Yan, L., Mieulet, V., Burgess, D., Findlay, G. M., Sully, K., Procter, J., Goris, J., Janssens, V., Morrice, N. A., Lamb, R. F.

Principal Investigator(s):
Greg Findlay
2010
PubMed

Mec1/Tel1-dependent phosphorylation of Slx4 stimulates Rad1-Rad10-dependent cleavage of non-homologous DNA tails

Toh, G. W., Sugawara, N., Dong, J., Toth, R., Lee, S. E., Haber, J. E., Rouse, J.

Principal Investigator(s):
John Rouse
2010
PubMed

Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation

Sanchez Canedo, C., Demeulder, B., Ginion, A., Bayascas, J. R., Balligand, J. L., Alessi, D. R., Vanoverschelde, J. L., Beauloye, C., Hue, L., Bertrand, L.

Principal Investigator(s):
Dario Alessi
2010
PubMed

SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na(+)-K(+)-Cl(-) cotransporter 2

Reiche, J., Theilig, F., Rafiqi, F. H., Carlo, A. S., Militz, D., Mutig, K., Todiras, M., Christensen, E. I., Ellison, D. H., Bader, M., Nykjaer, A., Bachmann, S., Alessi, D., Willnow, T. E.

Principal Investigator(s):
Dario Alessi
2010
PubMed

Role of the WNK-activated SPAK kinase in regulating blood pressure

Rafiqi, F. H., Zuber, A. M., Glover, M., Richardson, C., Fleming, S., Jovanovic, S., Jovanovic, A., O'Shaughnessy, K. M., Alessi, D. R.

Principal Investigator(s):
Dario Alessi
2010
PubMed

Phosphorylation of STIM1 at ERK1/2 target sites modulates store-operated calcium entry

Pozo-Guisado, E., Campbell, D. G., Deak, M., Alvarez-Barrientos, A., Morrice, N. A., Alvarez, I. S., Alessi, D. R., Martin-Romero, F. J.

Principal Investigator(s):
Dario Alessi
2010
PubMed